Genotypic Distribution of Hcv in Northeren India

Abstract

Introduction: Viral hepatitis is recognized as a public health problem in India and globally. Various etiological agents (Hepatitis A, B, C, D, E and G virus) have been implicated that can lead to acute, chronic or acute on chronic infection. While Hepatitis A and E are often the cause of sporadic outbreaks of hepatitis, Hepatitis B and C can either clear spontaneously or can lead to chronic infection and thereafter sequel like cirrhosis and hepatocellular carcinoma (HCC). Aims & objectives: To determine the genotyping of HCV infections among chronic hepatitis patients attending Department of Gastroenterology, PGIMS Rohtak. Summary and conclusions Our study confirms the finding of previous studies that in India Genotype 3 is most common genotype which is difficult to treat Genotype with oral antiviral therapy. Hence as per World Health Organization target of elimination of Hepatitis C till 2030 requires continuous, persistent and determined efforts at level of Center, State and society level.