Low Oocyte Maturity Rate and Asynchronous Follicle Development: Other Unnoticed Groups in the Bologna Criteria for Poor Responders?

Abstract

oocyte follicle the in vitro maturation, natural cycle, natural cycle preimplantation genetic testicular sperm for fertilization oocyte of oocytes the intracytoplasmic The The counts of total and oocytes and 7.3±4.5, respectively. A mean count of 2.38 embryos was transferred in 10118 cycles. The group 3 patients had a considerably higher live birth ratio compared to the group 1 and 2. Conclusion: We propose oocyte maturity rate and the count of M-II oocytes as two diagnostic criteria for the case definition of asynchronous follicle growth. Based on our findings, stimulation cycles ending with low oocyte maturity rate (≤50%) and ≤3 M-II oocytes would be considered asynchronous follicle development. Patients with low oocyte maturity rate and asynchronous follicle development should be counseled and informed regarding potential poor prognosis of the treatment. ABSTRACT live birth. In the prediction of live birth; the area under the ROC curve was 0.684 [95% confidence interval (CI): 0.671-0.697] for the count of mature oocytes and 0.653 (95% CI: 0.639-0.666) for the entire count of retrieved oocytes. These results showed that the count of M-II oocytes was better predictive of live birth than the entire count of harvested oocytes (p=0.0007).