Microsurgery for subtentorial cavernous malformations in children

Q4 Medicine

中华神经外科杂志 Pub Date : 2019-10-28 DOI:10.3760/CMA.J.ISSN.1001-2346.2019.10.013

Zhipeng Shen, H. Zeng, Wujie Shi, Peiliang Zhang, Jianbin Weng, Chao Lin

{"title":"Microsurgery for subtentorial cavernous malformations in children","authors":"Zhipeng Shen, H. Zeng, Wujie Shi, Peiliang Zhang, Jianbin Weng, Chao Lin","doi":"10.3760/CMA.J.ISSN.1001-2346.2019.10.013","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate the safety and efficacy of microsurgery in the treatment of subtentorial cavernous malformations (CMs) in children. \n \n \nMethods \nFrom June 2015 to June 2018, 12 patients (14 lesions) with pathologically proven subtentorial CMs at Department of Neurosurgery, the Children′s Hospital, Zhejiang University School of Medicine, were retrospectively enrolled into this study. The lesions were located in the brainstem in 4 cases and cerebellum in 8 cases (2 of them have 2 lesions in each). The brainstem lesions were examined by diffusion tensor imaging before operation. The safety and effectiveness of the operation were evaluated based on imaging examination, improvement of nervous system symptoms and modified Rankin scale (mRS). \n \n \nResults \nOf the 14 lesions, 13 were totally resected and 1 was followed up. During hospitalization, 9 of 12 cases with preoperative symptoms were improved, 2 cases kept preoperative symptoms and 1 case died. No new neurological deficits occurred. Eleven cases were followed up for 3 to 34 months. No re-bleeding or recurrence was found in the primary site of the lesion. The mRS scores were 0 in 9 cases, 1 in 1 and 2 in 1. \n \n \nConclusion \nUnder the premise of safety, surgical treatment of children′s subtentorial CMs is effective. \n \n \nKey words: \nHemangioma, cavernous; Central nervous system; Microsurgery; Child; Subtentorial","PeriodicalId":10100,"journal":{"name":"中华神经外科杂志","volume":"35 1","pages":"1027-1030"},"PeriodicalIF":0.0000,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华神经外科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1001-2346.2019.10.013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective To investigate the safety and efficacy of microsurgery in the treatment of subtentorial cavernous malformations (CMs) in children. Methods From June 2015 to June 2018, 12 patients (14 lesions) with pathologically proven subtentorial CMs at Department of Neurosurgery, the Children′s Hospital, Zhejiang University School of Medicine, were retrospectively enrolled into this study. The lesions were located in the brainstem in 4 cases and cerebellum in 8 cases (2 of them have 2 lesions in each). The brainstem lesions were examined by diffusion tensor imaging before operation. The safety and effectiveness of the operation were evaluated based on imaging examination, improvement of nervous system symptoms and modified Rankin scale (mRS). Results Of the 14 lesions, 13 were totally resected and 1 was followed up. During hospitalization, 9 of 12 cases with preoperative symptoms were improved, 2 cases kept preoperative symptoms and 1 case died. No new neurological deficits occurred. Eleven cases were followed up for 3 to 34 months. No re-bleeding or recurrence was found in the primary site of the lesion. The mRS scores were 0 in 9 cases, 1 in 1 and 2 in 1. Conclusion Under the premise of safety, surgical treatment of children′s subtentorial CMs is effective. Key words: Hemangioma, cavernous; Central nervous system; Microsurgery; Child; Subtentorial

查看原文本刊更多论文

儿童幕下海绵畸形的显微外科治疗

目的探讨显微外科手术治疗儿童窦下海绵状畸形的安全性和有效性。方法回顾性分析2015年6月至2018年6月浙江大学医学院儿童医院神经外科12例（14个病灶）经病理证实的颅内CMs患者。病变位于脑干4例，小脑8例（其中2例各有2处病变）。术前应用扩散张量成像检查脑干病变。根据影像学检查、神经系统症状改善和改良Rankin量表（mRS）评估手术的安全性和有效性。结果14个病灶中，13个全部切除，1个随访。在住院期间，12例术前症状改善的患者中有9例，2例保持术前症状，1例死亡。没有出现新的神经系统缺陷。11例随访3～34个月。病变原发部位未发现再出血或复发。mRS评分分别为0分9例、1分1例和2分1例。结论在安全的前提下，手术治疗儿童眶下CMs是有效的。关键词：血管瘤，海绵状；中枢神经系统；显微外科；儿童；地下室

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

中华神经外科杂志 Medicine-Surgery

CiteScore

0.10

自引率

0.00%

发文量

10706

期刊介绍： Chinese Journal of Neurosurgery is one of the series of journals organized by the Chinese Medical Association under the supervision of the China Association for Science and Technology. The journal is aimed at neurosurgeons and related researchers, and reports on the leading scientific research results and clinical experience in the field of neurosurgery, as well as the basic theoretical research closely related to neurosurgery.Chinese Journal of Neurosurgery has been included in many famous domestic search organizations, such as China Knowledge Resources Database, China Biomedical Journal Citation Database, Chinese Biomedical Journal Literature Database, China Science Citation Database, China Biomedical Literature Database, China Science and Technology Paper Citation Statistical Analysis Database, and China Science and Technology Journal Full Text Database, Wanfang Data Database of Medical Journals, etc.