Simulation of Leksell Gamma Knife-4C System with Different Phantoms Using PHITS and Geant4

IF 0.6 Q4 NUCLEAR SCIENCE & TECHNOLOGY

Atom Indonesia Pub Date : 2023-03-27 DOI:10.55981/aij.2023.1266

B. T. Hung, T. T. Dương, B. N. Hà

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引用次数: 0

Abstract

This study used PHITS and Geant4 code packages to simulate a Leksell Gamma Knife system in order to determine radiation dose distribution in two types of phantoms. The results observed in the water phantom with configurations of single source and 201 sources are in good accord with the prior research, including both simulation and experiment. Several characteristics of Leksell Gamma Knife 4C, such as dose profiles, output factor, FWHM, and penumbra size, are calculated based on Monte Carlo simulations, which show the best consistency with other results. The output factors for collimators of 14 mm, 8 mm, and 4 mm are 0.984, 0.949, and 0.872, respectively. The simulation results with an adult mesh-type reference phantom reveal considerable similarities with the established radiosurgery plans. It indicates that the absorbed dose in brain tumors was highest when utilizing the 18 mm collimator and subsequently reduced with collimator size to 0.65, 0.25, and 0.5 with the 14 mm, 8 mm, and 4 mm collimators, respectively. The absorbed dose has a very low value for other essential organs and decreases with distance from the brain tumor. These findings may explain why the dose to organs decreases linearly as target distance, volume, and collimator size increase.

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基于PHITS和Geant4的Leksell伽玛刀- 4c系统不同幻像的仿真

本研究使用PHITS和Geant4代码包模拟Leksell伽玛刀系统，以确定两种类型的幻影中的辐射剂量分布。在单声源和201声源配置的水影中，模拟和实验结果与前人的研究结果吻合较好。基于蒙特卡罗模拟计算了Leksell伽玛刀4C的剂量分布、输出因子、频宽、半影尺寸等特性，结果与其他结果一致。14 mm、8 mm和4 mm准直器的输出系数分别为0.984、0.949和0.872。成人网格型参考模型的仿真结果与所建立的放射手术方案有很大的相似之处。结果表明，当使用18 mm准直器时，脑肿瘤的吸收剂量最高，随后随着准直器尺寸的减小，分别为0.65,0.25和0.5，使用14 mm, 8 mm和4 mm准直器。其他重要器官的吸收剂量值很低，并且随着离脑肿瘤的距离而减少。这些发现可以解释为什么器官的剂量随着靶距离、体积和准直器尺寸的增加而线性降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Atom Indonesia NUCLEAR SCIENCE & TECHNOLOGY-

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： The focus of Atom Indonesia is research and development in nuclear science and technology. The scope of this journal covers experimental and analytical research in nuclear science and technology. The topics include nuclear physics, reactor physics, radioactive waste, fuel element, radioisotopes, radiopharmacy, radiation, and neutron scattering, as well as their utilization in agriculture, industry, health, environment, energy, material science and technology, and related fields.