Alternatives to Pharmacological and Psychotherapeutic Treatments in Psychiatric Disorders

IF 1.2 Q4 PSYCHIATRY
I. Vetrano, G. Bonomo, G. Messina
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引用次数: 3

Abstract

Nowadays, most of the patients affected by psychiatric disorders are successfully treated with psychotherapy and pharmacotherapy. Nevertheless, according to the disease, a variable percentage of patients results resistant to such modalities, and alternative methods can then be considered. The purpose of this review is to summarize the techniques and results of invasive modalities for several treatment-resistant psychiatric diseases. A literature search was performed to provide an up-to-date review of advantages, disadvantages, efficacy, and complications of Deep-Brain Stimulation, Magnetic Resonance-guided Focused-Ultrasound, radiofrequency, and radiotherapy lesioning for depression, obsessive-compulsive disorder, schizophrenia, addiction, anorexia nervosa, and Tourette’s syndrome. The literature search did not strictly follow the criteria for a systematic review: due to the large differences in methodologies and patients’ cohort, we tried to identify the highest quality of available evidence for each technique. We present the data as a comprehensive, narrative review about the role, indication, safety, and results of the contemporary instrumental techniques that opened new therapeutic fields for selected patients unresponsive to psychotherapy and pharmacotherapy.
精神疾病药物和心理治疗的替代方案
目前,大多数受精神障碍影响的患者都能通过心理治疗和药物治疗获得成功。然而,根据疾病的不同,不同比例的患者对这些方法产生抗药性,然后可以考虑其他方法。本综述的目的是总结几种难治性精神疾病的侵入性模式的技术和结果。通过文献检索,对深部脑刺激、磁共振引导聚焦超声、射频和放疗治疗抑郁症、强迫症、精神分裂症、成瘾、神经性厌食症和图雷特综合征的优点、缺点、疗效和并发症进行了最新综述。文献检索没有严格遵循系统评价的标准:由于方法和患者队列的巨大差异,我们试图为每种技术确定最高质量的可用证据。我们将这些数据作为一项全面的叙述性回顾,介绍当代仪器技术的作用、适应症、安全性和结果,这些技术为选定的对心理治疗和药物治疗无反应的患者开辟了新的治疗领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
0
审稿时长
11 weeks
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