Early clinical manifestations and pulmonary imaging analysis of patients with Novel coronavirus pneumonia/ 中华急诊医学杂志

Q4 Nursing

中华急诊医学杂志 Pub Date : 2020-02-09 DOI:10.3760/CMA.J.ISSN.1671-0282.2020.0005

Tao Yang, Xiaona Yu, Xingxing He, Wei Zhou, Yifu Fu, Q. Feng

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引用次数: 6

Abstract

Objective To investigate the early clinical characteristics and radiographic changes in confirmed Novel coronavirus pneumonia (NCP) and excluded NCP patients. Methods Twenty-four patients with suspected NCP admitted to Shanghai Jiao Tong University Affiliated Sixth People’s Hospital and Jinshan Branch Hospital between January and February, 2020 were chosen as our research subjects. Early clinical features and radiographic changes were analyzed in 10 patients of confirmed NCP and 14 patients of excluded NCP. Results In the early stage, all 24 suspected patients were mild, and had normal blood gas analysis. Of 10 diagnosed patients, 50% were male. All the 10 patients had fever and fatigue, with body temperature between 37.5℃ and 38.5℃. Only 1 patient had dry cough. 2 patients had no clear epidemiological exposure history, the other 8 had a clear epidemiological exposure, with a possible incubation period of 1-10 days. From CT imaging, lesions were characterized as ground glass shadow (n=9), which could be unilateral (n=1) or bilateral (n=9), and were mainly close to the pleura (n=9), with nodule shadow (n=1) and without focal necrosis, and could combined with pleural effusion (n=1. Among patients excluded NCP, all 14 patients had a clear history of epidemic exposure, with an onset time of 1 to 13 days. 12 patients had fever , including 4 with temperature > 38.5°C, 8 with temperature 37.3-38.5°C, and 2 without fever. All patients had fatigue , 7 patients had dry cough and 2 patients had chest pain. From CT imaging, ground glass shadow appeared in 4 patients , lesions were unilateral in 10 patients and bilateral in 4 patients , and the lesions were relatively sporadic, without necrosis or pleural effusion. Conclusion 1．Not all patients with NCP have a direct history of epidemiology exposure, some patients may be infected unknowingly. 2. According to CT imaging, NCP seems to have no special manifestations different from other viral pneumonia. 3. NCP is more common among middle-aged people. Key words: Novel coronavirus pneumonia; Clinical manifestations; Radiographic changes

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Early clinical manifestations and pulmonary imaging analysis of patients with Novel coronavirus pneumonia/ 中华急诊医学杂志

目的探讨确诊和排除的新型冠状病毒肺炎(NCP)患者的早期临床特征和影像学改变。方法选择2020年1 - 2月在上海交通大学附属第六人民医院和金山分院住院的24例疑似新型冠状病毒感染患者作为研究对象。分析10例确诊的新型冠状病毒感染患者和14例未确诊的新型冠状病毒感染患者的早期临床特征和影像学改变。结果24例疑似患者早期症状轻微，血气分析正常。在10例确诊患者中，50%为男性。10例患者均有发热、乏力，体温在37.5 ~ 38.5℃之间。仅有1例出现干咳。2例无明确流行病学暴露史，8例有明确流行病学暴露史，潜伏期可能为1 ~ 10天。CT表现为磨玻璃影(n=9)，可单侧(n=1)或双侧(n=9)，以靠近胸膜为主(n=9)，伴结节影(n=1)，无局灶性坏死，可合并胸腔积液(n=1)。在排除新型冠状病毒感染的患者中，14例患者均有明确的疫情暴露史，发病时间为1 ~ 13天。发热12例，其中4例体温bb0 38.5℃，8例体温37.3 ~ 38.5℃，2例无发热。所有患者均有疲劳，干咳7例，胸痛2例。CT表现:4例患者出现磨玻璃影，病变单侧10例，双侧4例，病变相对散发性，无坏死、胸膜积液。结论1。并非所有新冠肺炎患者都有直接的流行病学暴露史，有些患者可能在不知情的情况下被感染。2. 从CT影像来看，新冠肺炎似乎没有与其他病毒性肺炎不同的特殊表现。3.新冠肺炎在中年人中更为常见。关键词:新型冠状病毒肺炎;临床表现;影像学改变

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来源期刊

中华急诊医学杂志 Nursing-Emergency Nursing

CiteScore

0.10

自引率

0.00%

发文量

8629

期刊介绍： Chinese Journal of Emergency Medicine is the only national journal which represents the development of emergency medicine in China. The journal is supervised by China Association of Science and Technology, sponsored by Chinese Medical Association, and co-sponsored by Zhejiang University. The journal publishes original research articles dealing with all aspects of clinical practice and research in emergency medicine. The columns include Pre-Hospital Rescue, Emergency Care, Trauma, Resuscitation, Poisoning, Disaster Medicine, Continuing Education, etc. It has a wide coverage in China, and builds up communication with Hong Kong, Macao, Taiwan and international emergency medicine circles.