AN EVALUATION OF TREATMENT OUTCOME IN TUBERCULOSIS DIRECTLY OBSERVED TREATMENT SHORT COURSE FACILITIES IN JIGAWA STATE, NIGERIA (2010–2014)

Q4 Medicine
C. Moniruddin, M. Faisal, C. AbmAlauddin, H. Md.Imdadul
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Abstract

Tuberculosis (TB) is a major public health problem worldwide. It is estimated that 2 billion people, a third of the world population, have TB infection, but are not down with the disease.  Globally, incident cases of TB showed a rising trend, with a 6.6 million reported in 1990, 8.3 million in 2000, 9.24 million in 2004, and an estimated 9.27 million incident cases in 2007. The aim of this study was to evaluate the treatment outcome of TB patients in Nigeria in the state of Jigawa. A cross sectional retrospective study was conducted to evaluate the treatment outcome in directly observed treatment with a short course for tuberculosis (TB DOTS) in facilities in the state between the years 2010 to 2014. The study population were all the patients with TB, who had access to DOTS therapy. Data were collected from the various local governmental areas for tuberculosis control (LGA TB) register. The LGA TB control registers contained basic information of the patients, and a statistical software SPSS-V22.0 was used to analyse the data. A total of 963 TB patients were studied.  More than half (57.4%) of the patients were male, and nearly three- fourths (71.2%) of the patients accessed care from urban local government areas in the state. The greater majority (96.3%) of the cases had pulmonary tuberculosis (PTB). Among the patients, more than two-fifths (45%) were cured, and a little over one-fifth (20.6%) of them were HIV positive. This study revealed that the treatment success rate (TSR) in the Jigawa State of Nigeria was higher than the overall TSR of Nigeria, and the defaulter rate in this state was lower than the Nigerian average.
2010-2014年尼日利亚吉加瓦州结核病直接观察短期治疗设施治疗效果评估
结核病(TB)是世界范围内的一个主要公共卫生问题。据估计,有20亿人(占世界人口的三分之一)感染了结核病,但病情并未下降。在全球范围内,结核病发病率呈上升趋势,1990年报告为660万例,2000年为830万例,2004年为924万例,2007年估计为927万例。本研究的目的是评估尼日利亚吉加瓦州结核病患者的治疗结果。本研究采用横断面回顾性研究,评估2010年至2014年在该州各机构直接观察短程结核病治疗(TB DOTS)的治疗效果。研究人群为所有接受DOTS治疗的结核病患者。数据收集自各个地方政府地区的结核病控制(LGA TB)登记册。LGA结核控制登记簿包含患者的基本信息,采用SPSS-V22.0统计软件对数据进行分析。共对963例结核病患者进行了研究。超过一半(57.4%)的患者是男性,近四分之三(71.2%)的患者从该州的城市地方政府区域获得护理。绝大多数病例(96.3%)为肺结核(PTB)。在患者中,超过五分之二(45%)的人被治愈,超过五分之一(20.6%)的人是HIV阳性。本研究显示,尼日利亚吉加瓦州的治疗成功率(TSR)高于尼日利亚的总体TSR,该州的违约率低于尼日利亚的平均水平。
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