Post COVID-19 Disseminated Mucormycosis in a 55-year-old patient in Western Amazon: Case report

Q2 Medicine
Sebastião Afonso Viana Macedo Neves, Lidyane Liadja Souza Silva, Rosely Antunes Patzina, Cesar Cilento Ponce, Jordy Souza Cordeiro, Aline Oliveira de Araújo, Evelyn Lepka de Lima, Irenilce Souza de Matos, Juvencio José Duailibe Furtado, Letícia Varize Pussi, Erine Aragão Cavalcante, Marcos Vinícius da Silva
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引用次数: 1

Abstract

A feared fungal disease surprised and became a warning to severe cases of COVID-19, especially to health professionals involved with the pandemic. Designated as black fungus for public health services in India, where reported data reflects an increase of more than eighty times the expected increase for Rhizopus among the communities. The disease has become even more worrisome due to the high mortality already established as an opportunistic infection, coupled with the reserved prognosis for all those infected and hospitalised by the SARS-CoV-2 severity criteria. This patient, who was submitted to corticosteroid therapy, in an excessive dose, therefore immunosuppressive, developed a severe, disseminated clinical form. It was verified the progression of the lesions and thus the high risk of trans- surgical lethality, or, also, by the insufficiency of conduct in removing the lesions to their satisfaction. Thus, the therapeutic option is the associated use of micafungin, liposomal amphotericin B and isavuconazole for the regressive phase. The patient remains hospitalised with progressive and discrete improvement. Until the opportunity of reevaluation of the surgery by the interspecialty collaboration.
西亚马逊地区1例55岁患者COVID-19后播散性毛霉菌病病例报告
一种令人恐惧的真菌疾病令人惊讶,并成为对COVID-19严重病例的警告,特别是对参与大流行的卫生专业人员。在印度被指定为公共卫生服务的黑菌类,在那里报告的数据反映根霉在社区中的增长是预期增长的80多倍。由于已经确定为机会性感染的高死亡率,加上根据SARS-CoV-2严重程度标准对所有感染者和住院患者的预后保留,这种疾病变得更加令人担忧。该患者接受皮质类固醇治疗,剂量过大,因此免疫抑制,出现严重的弥散性临床症状。这证实了病变的进展,因此有很高的经手术死亡率,或者,也可能是由于在切除病变方面的行为不足而使他们满意。因此,治疗选择是在退行期联合使用米卡芬金、两性霉素B脂质体和异唑康唑。患者仍在住院,病情有进行性和离散性改善。直到有机会通过跨专业合作对手术进行重新评估。
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来源期刊
Journal of Human Growth and Development
Journal of Human Growth and Development Social Sciences-Life-span and Life-course Studies
CiteScore
2.70
自引率
0.00%
发文量
37
审稿时长
22 weeks
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