Phytochemical analysis, antibacterial activity and antibiotic modifying action of Jatropha mollissima (Pohl.) Baill. (Euphorbiaceae)

Anales de Biologia Pub Date : 2020-06-15 DOI:10.6018/analesbio.42.10

Noelly Bastos-Cavalcante, Cristina Rodrigues dos Santos-Barbosa, Raimundo Luiz Silva-Pereira, Débora Feitosa-Muniz, Henrique Douglas de Melo-Coutinho, Larissa Araújo-Rolim, J. Almeida

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引用次数: 3

Abstract

La aparición de cepas bacterianas resistentes y los efectos secundarios de sus fármacos disponibles han hecho investigar nuevos compuestos antibacterianos bioactivos. Jatropha mollissima es una planta endémica del bioma Caatinga, Brasil. Existen informes en la literatura de que esta especie tiene acción antioxidante, antibacteriana y antiproliferativa. El presente estudio tuvo como objetivo evaluar el potencial antibacteriano y modulador de J. mollissima contra cepas bacterianas multirresistentes. El perfil fitoquímico se obtuvo por cromatografía de gases junto con espectrometría de masas. J. mollissima mostró actividad antibacteriana moderada y moduló la actividad del antibiótico Norfloxacino, promoviendo una relación antagonista. Este fue el primer estudio de este tipo realizado con J. mollissima. The emergence of resistant bacterial strains and the significant increase in side effects of currently available antibacterial drugs have made it urgent to develop research to identify new bioactives antibacterial compounds. Jatropha mollissima is a plant endemic to the Caatinga biome, Brazil and this species has antioxidant, antibacterial and antiproliferative action. The present study aimed to evaluate the antibacterial and modulatory potentials of J. mollissima against multiresistant bacterial strains. The phytochemical profile was obtained from gas chromatography coupled to mass spectrometry. J. mollissima presented moderate antibacterial activity and modulated the activity of the antibiotic Norfloxacin, promoting an antagonistic relationship. This was the first study of this nature carried out with J. mollissima.

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麻疯树(Jatropha mollissima)的植物化学分析、抗菌活性及抗生素修饰作用Baill。(大戟科)

耐药菌株的出现及其现有药物的副作用促使人们对新的生物活性抗菌化合物进行研究。麻疯树是巴西Caatinga生物群落特有的一种植物。在文献中有报道称该物种具有抗氧化、抗菌和抗增殖作用。本研究的目的是评价mollissima对多重耐药菌株的抗菌和调节潜力。采用气相色谱-质谱法测定了植物化学特征。mollissima表现出适度的抗菌活性，调节抗生素诺氟沙星的活性，促进拮抗关系。这是对J. mollissima进行的第一次此类研究。耐药菌株的出现和现有抗菌药物副作用的显著增加，使得迫切需要开展研究，以确定新的生物活性抗菌化合物。麻疯树是巴西Caatinga生物区的一种特有植物，具有抗氧化、抗细菌和抗繁殖作用。本研究旨在评价mollissima对多重耐药菌株的抗菌和调节潜力。= =地理= =根据美国人口普查，该镇的总面积为，其中土地和(0.964平方公里)水。j . mollissima介绍了抗菌辐射计activity and modulated the activity of the antibiotic Norfloxacin,促进建立一个antagonistic relationship。= =地理= =根据美国人口普查，该镇的土地面积为。

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来源期刊

Anales de Biologia

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审稿时长

12 weeks