Aplastic anemia in pregnancy

Abstract

Aplastic anemia (AA) is a rare hematological disorder which is life-threatening in pregnancy. It is mainly caused by the destruction of pluripotent stem cells of bone marrow. There is high risk in pregnancy due to risk of hemorrhage and infection due to pancytopenia. Fetus is also at high risk of intrauterine growth restriction, risk of intrauterine death, and preterm labor. Hence, managing aplastic anemia in pregnancy is a great challenge for obstetricians. It requires a multidisciplinary approach involving hematologist, obstetrician, and critical care specialist for the management of AA in pregnancy. We report a case of AA with pregnancy diagnosed during first trimester.