5‑Sulphosalicylic acid: An expeditious Organocatalyst for one‑pot synthesis of Indenopyrazolones and its derivatives

IF 0.9 Q4 CHEMISTRY, PHYSICAL

Current Organocatalysis Pub Date : 2023-06-09 DOI:10.2174/2213337210666230609150318

Archana Jyoti, Smriti Kushwaha, Swastika Singh, J. Baranwal

引用次数: 0

Abstract

An efficient, 5‑Sulphosalicylic acid (5- SSA) catalysed green protocol for the synthesis of Indenopyrazolones and its derivatives is reported under metal-free conditions in an ethyl lactate system. The main advantages of this procedure include the use of an organocatalyst, ethyl lactate as a recyclable promoting media, practical simplicity, high yields, shorter reaction times, atom economy, and ease of isolation of the product. These results showed that aromatic aldehydes with electron-withdrawing groups reacted faster than aldehydes with electron-releasing groups as expected. According to these observations, aromatic aldehydes with electron-withdrawing groups reacted more quickly than aldehydes with electron-releasing groups.

查看原文本刊更多论文

5 -磺酰水杨酸:一锅合成独立吡唑酮及其衍生物的快速有机催化剂

报道了一种高效的5-磺基水杨酸（5-SSA）催化的绿色方案，用于在无金属条件下在乳酸乙酯系统中合成茚吡唑酮及其衍生物。该方法的主要优点包括使用有机催化剂，乳酸乙酯作为可回收的促进介质，实用简单，高产率，更短的反应时间，原子经济性，以及易于分离产物。这些结果表明，如预期的那样，具有吸电子基团的芳香醛比具有电子释放基团的醛反应更快。根据这些观察结果，具有吸电子基团的芳香醛比具有电子释放基团的醛反应更快。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Organocatalysis CHEMISTRY, PHYSICAL-

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.