Durability of Bioprosthetic Valves in Patients on Dialysis

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
T. Uzuka, Masanori Nakamura, Hirotaro Sugiyama, Mayo Kondo, J. Sakata
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引用次数: 1

Abstract

Purpose: This study focused on clarifying the durability of bioprosthetic valves in current practice. Methods: A total of 238 consecutive patients who underwent aortic valve replacement at a single institution from 2011 to 2020 were reviewed. We evaluated valve-related outcomes such as structural valve deterioration (SVD), especially in dialysis patients who received bioprosthetic valve. Results: Among the tissue valves implanted in 212 patients, 5 SVDs were recorded and 3 valves were replaced. All early valve failures occurred in relatively young dialysis patients and were recorded 3 to 5 years after the initial operation. Freedom from SVD at 6 years was 49.9% in patients on dialysis, compared with 100% in non-dialysis patients. Predictors of better survival in dialysis patients were better preoperative functional class and larger prosthetic valve size. Conclusions: The durability of bioprosthetic valves in the aortic position was suboptimal in dialysis patients. Mechanical valves can be an option for young, healthy dialysis patients with a large aortic valve annulus.
透析患者生物假体瓣膜的耐久性
目的:本研究旨在阐明生物瓣膜在当前实践中的耐用性。方法:对2011年至2020年在单一机构接受主动脉瓣置换术的238名连续患者进行回顾性分析。我们评估了瓣膜相关的结果,如结构瓣膜恶化(SVD),尤其是接受生物瓣膜的透析患者。结果:在212例植入的组织瓣膜中,记录了5例SVD,并更换了3例瓣膜。所有早期瓣膜失效均发生在相对年轻的透析患者中,并在初次手术后3至5年记录在案。接受透析的患者在6年时免于SVD的发生率为49.9%,而非透析患者为100%。透析患者生存率较高的预测因素是术前功能级别较好和人工瓣膜尺寸较大。结论:生物瓣膜在主动脉位置的耐久性在透析患者中是次优的。对于患有大主动脉瓣环的年轻健康透析患者,机械瓣膜是一种选择。
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来源期刊
Annals of Thoracic and Cardiovascular Surgery
Annals of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.80
自引率
0.00%
发文量
56
审稿时长
4-8 weeks
期刊介绍: Information not localized
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