Surface-modified substrates for the Langmuir-Blodgett deposition of patterned ultra-thin and highly oriented collagen coatings

IF 1 4区工程技术 Q4 ENGINEERING, MECHANICAL

International Journal of Surface Science and Engineering Pub Date : 2019-02-25 DOI:10.1504/IJSURFSE.2019.10019180

Karina Ambrock, B. Grohe, S. Mittler

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Abstract

As a pre-study for highly oriented collagen coatings on implants (with irregular surfaces and shapes), the Langmuir-Blodgett (LB) technology, a low-cost and straightforward approach, was pioneered. The effects of physicochemical (hydrophilic/hydrophobic) patterns and 3D-mechanical barriers present on substrate surfaces are studied in terms of the dynamics of collagen flow during LB film deposition and the formation of highly oriented coatings. Due to the large internal cohesion of collagen films, only large 3D-obstacles deflect the flow of collagen and lead to film rupture, suggesting that objects (screw-threaded dental implants) with small topographic features should be easily and evenly coatable. Moreover, hydrophilic/hydrophobic/collagen patterned substrate surfaces were fabricated, by partly removing coated collagen. These substrates are outstanding for timely studies that need identical conditions but different surface properties side by side. Crystallisation of barium oxalate was carried out as a proof-of-principle.

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用于Langmuir-Blodgett沉积图案化超薄和高取向胶原涂层的表面改性基底

作为植入物(不规则表面和形状)上高度定向胶原蛋白涂层的预研究，Langmuir-Blodgett (LB)技术是一种低成本和直接的方法。根据LB膜沉积过程中胶原流动的动力学和高取向涂层的形成，研究了基材表面存在的物理化学(亲水/疏水)模式和3d机械屏障的影响。由于胶原膜具有较大的内聚性，只有较大的3d障碍物才会使胶原蛋白的流动发生偏转，导致膜破裂，提示具有较小地形特征的物体(螺纹种植体)应易于均匀涂覆。此外，通过部分去除涂层的胶原蛋白，制备了亲水/疏水/胶原蛋白图案的底物表面。这些衬底对于需要相同条件但不同表面特性的及时研究是杰出的。草酸钡的结晶是作为一种原理证明。

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来源期刊

International Journal of Surface Science and Engineering 工程技术-材料科学：膜

CiteScore

1.60

自引率

25.00%

发文量

审稿时长

>12 weeks

期刊介绍： IJSurfSE publishes refereed quality papers in the broad field of surface science and engineering including tribology, but with a special emphasis on the research and development in friction, wear, coatings and surface modification processes such as surface treatment, cladding, machining, polishing and grinding, across multiple scales from nanoscopic to macroscopic dimensions. High-integrity and high-performance surfaces of components have become a central research area in the professional community whose aim is to develop highly reliable ultra-precision devices.