Case report on ciprofloxacin induced occular toxicityXICITY

Sara Johny
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引用次数: 0

Abstract

CASE SUMMARY: A 75-year-old male patient was admitted to the Department of Ophthalmology for Cataract Surgery of his left eye. He was prescribed topical Ciprofloxacin 0.3% preoperatively four times daily for 5 consecutive days. After 4 days he had complaints of itching, redness and swelling in the periorbital area of the left eye. He visited the outpatient clinic and was admitted. Therapy was discontinued, and the physician prescribed medications to address symptoms. He recovered within one month.  DISCUSSION: Fluoroquinolones can elicit a delayed type of hypersensitivity reaction which is mainly T cell-mediated. Ocular toxicity commonly arises due to ciprofloxacin administration but is seldom reported. Swelling, redness and itching of the eye have been rarely reported. The exact mechanism behind such an adverse drug reaction is unknown and might be due to patient hypersensitivity to the fluroquinolone group of antibiotics. CONCLUSION:  Topical ciprofloxacin medications may lead to ocular toxicity and caution is needed while using these eye drops in patients. Also, these kinds of adverse reactions must be carefully reported.
环丙沙星致球菌毒性病例报告XICITY
病例摘要:一名75岁男性患者因左眼白内障手术被送入眼科。术前给他开了0.3%的局部环丙沙星,每天4次,连续5天。4天后,他出现左眼眶周瘙痒、红肿的症状。他去了门诊部并入院了。停止了治疗,医生开了药物来治疗症状。他不到一个月就康复了。讨论:氟喹诺酮类药物可引发一种延迟型超敏反应,主要由T细胞介导。眼部毒性通常由环丙沙星引起,但很少报道。眼睛肿胀、发红和瘙痒的报道很少。这种药物不良反应背后的确切机制尚不清楚,可能是由于患者对氟喹啉类抗生素过敏。结论:局部服用环丙沙星可能导致眼部毒性,患者在使用这些滴眼液时需要谨慎。此外,必须仔细报告此类不良反应。
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来源期刊
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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