{"title":"Case report on ciprofloxacin induced occular toxicityXICITY","authors":"Sara Johny","doi":"10.22038/APJMT.2020.17415","DOIUrl":null,"url":null,"abstract":"CASE SUMMARY: A 75-year-old male patient was admitted to the Department of Ophthalmology for Cataract Surgery of his left eye. He was prescribed topical Ciprofloxacin 0.3% preoperatively four times daily for 5 consecutive days. After 4 days he had complaints of itching, redness and swelling in the periorbital area of the left eye. He visited the outpatient clinic and was admitted. Therapy was discontinued, and the physician prescribed medications to address symptoms. He recovered within one month. \nDISCUSSION: Fluoroquinolones can elicit a delayed type of hypersensitivity reaction which is mainly T cell-mediated. Ocular toxicity commonly arises due to ciprofloxacin administration but is seldom reported. Swelling, redness and itching of the eye have been rarely reported. The exact mechanism behind such an adverse drug reaction is unknown and might be due to patient hypersensitivity to the fluroquinolone group of antibiotics. \nCONCLUSION: Topical ciprofloxacin medications may lead to ocular toxicity and caution is needed while using these eye drops in patients. Also, these kinds of adverse reactions must be carefully reported.","PeriodicalId":30463,"journal":{"name":"Asia Pacific Journal of Medical Toxicology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia Pacific Journal of Medical Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/APJMT.2020.17415","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
CASE SUMMARY: A 75-year-old male patient was admitted to the Department of Ophthalmology for Cataract Surgery of his left eye. He was prescribed topical Ciprofloxacin 0.3% preoperatively four times daily for 5 consecutive days. After 4 days he had complaints of itching, redness and swelling in the periorbital area of the left eye. He visited the outpatient clinic and was admitted. Therapy was discontinued, and the physician prescribed medications to address symptoms. He recovered within one month.
DISCUSSION: Fluoroquinolones can elicit a delayed type of hypersensitivity reaction which is mainly T cell-mediated. Ocular toxicity commonly arises due to ciprofloxacin administration but is seldom reported. Swelling, redness and itching of the eye have been rarely reported. The exact mechanism behind such an adverse drug reaction is unknown and might be due to patient hypersensitivity to the fluroquinolone group of antibiotics.
CONCLUSION: Topical ciprofloxacin medications may lead to ocular toxicity and caution is needed while using these eye drops in patients. Also, these kinds of adverse reactions must be carefully reported.
期刊介绍:
Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.