Progress of long non-coding RNA in pituitary adenoma

Q4 Medicine

肿瘤研究与临床 Pub Date : 2020-01-28 DOI:10.3760/CMA.J.ISSN.1006-9801.2020.01.016

Jinke Ding, Chenglong Li, H. Wang

引用次数: 0

Abstract

Pituitary adenoma is a common neuroendocrine tumor, and its complex pathogenesis makes its treatment a clinical problem. Recently, studies have shown that long non-coding RNA (LncRNA), as a class of endogenous RNA with a length of more than 200 nucleotides and basically no protein-coding function, plays an important regulatory role in various forms in multiple tumors including pituitary adenoma, and is closely related to the proliferation, invasion and metastasis of pituitary adenoma. Based on the latest research status at home and abroad, this paper summarizes the research progress of LncRNA in pituitary adenoma, hoping to provide new ideas for the diagnosis, treatment and prognosis of pituitary adenoma. Key words: Neuroendocrine tumors; Brain neoplasms; Long non-coding RNA

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垂体腺瘤长非编码RNA研究进展

垂体腺瘤是一种常见的神经内分泌肿瘤，其复杂的发病机制使其治疗成为临床难题。近年来，研究表明，长非编码RNA（LncRNA）作为一类长度超过200个核苷酸、基本上没有蛋白质编码功能的内源性RNA，在包括垂体腺瘤在内的多种肿瘤中以多种形式发挥着重要的调节作用，与垂体腺瘤的增殖、侵袭和转移密切相关。本文结合国内外最新研究现状，综述了LncRNA在垂体腺瘤中的研究进展，希望为垂体腺瘤的诊断、治疗和预后提供新的思路。关键词：神经内分泌肿瘤；脑肿瘤；长非编码RNA

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

肿瘤研究与临床 Medicine-Oncology

CiteScore

0.10

自引率

0.00%

发文量

7737

期刊介绍： "Cancer Research and Clinic" is a series of magazines of the Chinese Medical Association under the supervision of the National Health Commission and sponsored by the Chinese Medical Association. It mainly reflects scientific research results and academic trends in the field of malignant tumors. The main columns include monographs, guidelines and consensus, standards and norms, treatises, short treatises, survey reports, reviews, clinical pathology (case) discussions, case reports, etc. The readers are middle- and senior-level medical staff engaged in basic research and clinical work on malignant tumors.