Trends in Time in Range-Related Publications and Clinical Trials: A Bibliometric Review.

Q3 Medicine
Diabetes Spectrum Pub Date : 2023-01-01 Epub Date: 2023-05-11 DOI:10.2337/ds22-0085
Pranav M Patel, Richard M Abaniel, Natasha Dogra, Charles B Lo, Marie A Frazzitta, Naunihal S Virdi
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引用次数: 0

Abstract

Objective: The goal of this article was to describe trends in publications (including conference abstracts) and clinical trials that report on glycemic time in range (TIR).

Data sources: Reviewed databases included but were not limited to MEDLINE and Embase. Clinical trial registries were also sourced.

Study selection: All studies reporting TIR published between 2010 and 2021 were included. Clinical trials reporting TIR that started in or after 2010 were also included. Non-English publications, abstracts, and clinical trials were excluded. Book chapters, nonhuman studies, and studies not reporting TIR were excluded.

Data extraction: Manuscript/abstract category, publication year, study region, interventional versus observational role of continuous glucose monitoring (CGM), and clinical trial start and completion dates were captured. Glycemic outcomes reported in publications or trials, including TIR as a primary outcome, A1C, time below range (TBR), and time above range (TAR), were also captured.

Results: A total of 373 clinical trials, 531 publications, and 620 abstracts were included in the review. The number of trials, publications, and abstracts reporting TIR significantly increased, particularly between 2018 and 2021, during which time the number of clinical trials, publications, and conference abstracts reporting TIR increased by 6-fold, 12-fold, and 4.5-fold, respectively. About 35-44% of studies reported TIR as a primary outcome. Approximately 54% of clinical trials, 47% of publications, and 47% of conference abstracts reported the role of CGM to be observational. TBR was reported more often than TAR.

Conclusion: The marked increase in the number of trials, publications, and abstracts reporting TIR highlights the increasing significance and acceptance of TIR as an outcome measure in diabetes management.

时间范围内的趋势——相关出版物和临床试验:文献计量学综述
本文的目的是描述出版物(包括会议摘要)和临床试验中报告血糖范围内时间(TIR)的趋势。所审查的数据库包括但不限于MEDLINE和Embase。临床试验登记处也得到了来源。纳入了2010年至2021年间发表的所有报告TIR的研究。2010年或之后开始的报告TIR的临床试验也包括在内。非英文出版物、摘要和临床试验被排除在外。排除了书籍章节、非人类研究和未报告TIR的研究。论文/摘要类别、发表年份、研究区域、持续血糖监测(CGM)的介入作用与观察作用、临床试验开始和完成日期均被记录。在出版物或试验中报告的血糖结局,包括作为主要结局的TIR、A1C、低于范围的时间(TBR)和高于范围的时间(TAR),也被捕获。该综述共纳入373项临床试验、531篇出版物和620篇摘要。报告TIR的试验、出版物和摘要的数量显著增加,特别是在2018年至2021年期间,在此期间,报告TIR的临床试验、出版物和会议摘要的数量分别增加了6倍、12倍和4.5倍。约35-44%的研究报告TIR为主要结局。大约54%的临床试验、47%的出版物和47%的会议摘要报道CGM的作用是观察性的。TBR的报告频率高于TAR。报告TIR的试验、出版物和摘要数量的显著增加,突显了TIR作为糖尿病管理结果衡量标准的重要性和接受度日益增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Diabetes Spectrum
Diabetes Spectrum Medicine-Internal Medicine
CiteScore
2.70
自引率
0.00%
发文量
62
期刊介绍: The mission of Diabetes Spectrum: From Research to Practice is to assist health care professionals in the development of strategies to individualize treatment and diabetes self-management education for improved quality of life and diabetes control. These goals are achieved by presenting review as well as original, peer-reviewed articles on topics in clinical diabetes management, professional and patient education, nutrition, behavioral science and counseling, educational program development, and advocacy. In each issue, the FROM RESEARCH TO PRACTICE section explores, in depth, a diabetes care topic and provides practical application of current research findings.
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