Change in Contrast Sensitivity among Patients with Diabetic Mellitus Type II

S. Shrestha, G. Prasai, R. Shrestha, O. K. Malla
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Abstract

Introduction: Eye being one of the target organs of diabetes mellitus has many pathological consequences, one possibly being contrast sensitivity. Contrast sensitivity is required for daily activities like in situations of low light, fog or driving at night. The study was conducted to find out contrast sensitivity among diabetic Methodology: A hospital based descriptive cross- sectional study of contrast sensitivity was conducted among type II diabetics with or without retinopathy at Kathmandu Medical College from April to December 2018. Patient demographics and comprehensive clinical examinations findings were recorded in a specially designed proforma. Convenience sampling was done and informed consent was taken. Leas symbol low contrast test 10M was used for contrast sensitivity testing. The contrast levels of the test lines on the five pages are 25%, 10%, 5%. 2.5%and 1.2%. Data was analyzed in excel and SPSS (version21). Results were expressed in frequency, percentage and mean as required. Association of contrast sensitivity with age, gender, duration of diabetes, blood sugar level and diabetic retinopathy was tested using chi square test. Results: Among the 45 study population, female to male ratio was 1:2. Age ranged from 25 to 76 years with maximum patients in the age group 51-60 years. Blood sugar was controlled in 33.33%. Contrast sensitivity was decreased in 40%. Among the patients with decreased contrast sensitivity, blood sugar was uncontrolled in 66.67%. Similarly, 72.2% of participants with decreased contrast sensitivity had no diabetic retinopathy. The association of contrast sensitivity with age of the patient, gender, duration of diabetes mellitus, blood sugar level and diabetic retinopathy was not statistically significant with p values 0.34, 0.52, 0.07, 1 and 0.89 respectively.                                                                                                                                                Conclusion: Contrast sensitivity can be decreased among patients with type II diabetes mellitus irrespective of gender, age of the patient, duration of diabetes, control of blood sugar and presence or absence of diabetic retinopathy.
2型糖尿病患者对比敏感性的变化
眼睛作为糖尿病的靶器官之一,有许多病理后果,其中一个可能是对比敏感性。对比度灵敏度需要在日常活动,如在低光,雾或夜间驾驶的情况下。方法:2018年4月至12月,在加德满都医学院对有或无视网膜病变的II型糖尿病患者进行了一项基于医院的对比敏感性描述性横断面研究。患者人口统计和综合临床检查结果记录在一个专门设计的形式。采用方便抽样并取得知情同意。对比灵敏度测试采用Leas符号低对比度测试10M。五页上测试线的对比水平分别为25%、10%、5%。2.5%和1.2%。数据分析采用excel和SPSS (version21)软件。结果按要求以频率、百分比和平均值表示。对比敏感度与年龄、性别、糖尿病病程、血糖水平及糖尿病视网膜病变的相关性采用卡方检验。结果:45例研究人群中,男女比例为1:2。患者年龄在25 ~ 76岁之间,最大患者年龄在51 ~ 60岁。血糖控制在33.33%。对比敏感度降低40%。对比敏感性降低的患者中,66.67%血糖不受控制。同样,对比敏感度降低的参与者中有72.2%没有糖尿病视网膜病变。对比敏感度的协会与病人的年龄,性别,时间糖尿病,血糖水平和糖尿病性视网膜病变没有统计学意义,p值0.34,0.52,0.07,1和0.89 .                                                                                                                                               结论:2型糖尿病患者不论性别、年龄、病程、血糖控制情况、有无糖尿病视网膜病变均可降低对比剂敏感性。
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