Neurological Manifestations of Hospitalized Patients with Covid-19: A Case Series Study

Q4 Medicine

Acta Medica Bulgarica Pub Date : 2021-10-01 DOI:10.2478/amb-2021-0035

M. Zamanian, A. Janbakhsh, F. Mansouri, B. Sayad, M. Afsharian, S. Vaziri, B. Mahdavian, Z. Afshar, R. Miladi, M. Shirvani, M. Noori, M. Salimi, A. Babazadeh, S. Ebrahimpour

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引用次数: 8

Abstract

Abstract There are some reports about the neurological manifestations and complications of COVID-19. We present neurological manifestations in 6 hospitalized patients with COVID-19. The patients presented with common symptoms of COVID-19 along with common findings from high-resolution computed tomography (HRCT) scan such as ground-glass opacities (GGOs). Though, RT-PCR testing of SARS-CoV-2 was negative for all 6 cases. In the current report, acute cerebrovascular diseases affected older patients, while dementia, seizure and encephalopathy affected younger ones. Three of the 6 patients had proven strokes based on their neuroimaging. Four of the 6 patients had high d-dimer levels. Two of the cases experienced convulsion. The third patient presented with typical symptoms and signs of neuroleptic malignant syndrome. The sixth case was interesting for transient dementia. Unfortunately, four out of six patients died. The recent case series report the association between neurological involvements and COVID-19 infection. Clinicians should be alert of the neurologic symptoms in the setting of COVID-19, which might even be the first presentations of this infection.

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新冠肺炎住院患者的神经学表现:病例系列研究

摘要目前有一些关于COVID-19的神经学表现和并发症的报道。我们报告了6例住院的COVID-19患者的神经学表现。患者表现出COVID-19的常见症状以及高分辨率计算机断层扫描(HRCT)的常见结果，如磨玻璃混浊(GGOs)。然而，所有6例病例的SARS-CoV-2 RT-PCR检测均为阴性。在目前的报告中，急性脑血管疾病影响老年人，而痴呆、癫痫和脑病影响年轻人。根据神经影像学检查，6名患者中有3名确诊为中风。6例患者中有4例d-二聚体水平高。其中两例出现抽搐。第三例患者表现出典型的抗精神病药恶性综合征的症状和体征。第六例是短暂性痴呆的有趣病例。不幸的是，6名患者中有4人死亡。最近的病例系列报告了神经系统受累与COVID-19感染之间的关联。临床医生应警惕COVID-19背景下的神经系统症状，这甚至可能是这种感染的首次表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Medica Bulgarica Medicine-Medicine (all)

CiteScore

0.30

自引率

0.00%

发文量

审稿时长

25 weeks

期刊介绍： About 30 years ago - in 1973, on the initiative of the Publishing House „Medicine and Physical Culture", namely its former director Mr. Traian Ivanov, the Ministry of Health set up and accepted to subsidize a new medical magazine that was to be published only in the English language and had to reflect the status and the achievements of the Bulgarian medical science. Thus the language barrier was overcome and stable relations were established with the international medical society, large libraries, and university centers. The famous internationally known scientist professor Assen A. Hadjiolov was elected edition-in-chief by the first editorial staff and the magazine was named Acta Medica Bulgarica.