A fatal disease hidden behind a common symptom: Neuromyelitis optica spectrum disorder

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
V. Sharma, A. Umashankar
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引用次数: 0

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder of the central nervous system. Recently, a number of clinical features have been identified in the diagnosis, and this disorder has been expanded to include a wider spectrum. It is important to have knowledge of these syndromes to diagnose this condition. One such presentation is intractable vomiting and hiccoughs, which is categorized as area postrema syndrome (APS) and is often misdiagnosed as a digestive disorder. We present a case of young female presenting with unresolving vomiting and hiccoughs. Magnetic resonance imaging done showed lesions in the dorsal medulla, suggestive of APS. A positive immunoglobulin G aquaporin-4 antibody confirmed the diagnosis of NMOSD. With this case report, we try to reiterate the importance of knowing the varied presentations of NMOSD and vigilance in identifying that a common symptom such as vomiting/hiccough can be due to an uncommon disorder.
一种隐藏在常见症状背后的致命疾病:视神经脊髓炎谱系障碍
神经脊髓炎视谱障碍(NMOSD)是一种中枢神经系统的炎症性脱髓鞘疾病。最近,在诊断中已经确定了一些临床特征,并且这种疾病已经扩展到包括更广泛的范围。了解这些症状对诊断这种疾病很重要。其中一种表现是顽固性呕吐和打嗝,这被归类为后遗症(APS),经常被误诊为消化系统疾病。我们提出一个年轻女性的情况下,表现为无法解决的呕吐和打嗝。磁共振成像显示髓质背侧病变,提示APS。免疫球蛋白G水通道蛋白-4抗体阳性证实了NMOSD的诊断。在此病例报告中,我们试图重申了解NMOSD的各种表现和警惕的重要性,以确定呕吐/打嗝等常见症状可能是由罕见疾病引起的。
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来源期刊
Indian Journal of Medical Specialities
Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-
自引率
16.70%
发文量
51
期刊介绍: The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.
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