A Previously Undescribed Cleistanthane-Type Diterpenoid from Peniophora incarnate

IF 1.5 4区生物学 Q3 CHEMISTRY, APPLIED

Records of Natural Products Pub Date : 2023-03-25 DOI:10.25135/rnp.374.2210.2619

Yun Deng, Mei-Mei Li, Wenxiu Guo, Congcong Li, Xue-yan Huo, Yunjie Hu, D. Guo, Li-jun Huang, Yu Jiang

引用次数: 0

Abstract

: A newly discovered cleistanthane-type diterpenoid named incarnatin A ( 1 ) was isolated from Peniophora incarnate , an endophytic fungus obtained from the roots of Ligusticum chuanxiong . Its absolute configuration was unambiguously elucidated by spectroscopic means including HRMS and NMR combined with ECD calculations. Transcriptome sequencing indicated that 1 could inhibit angiogenesis.

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一种先前未被描述过的从参属植物中提取的clestan烷型二萜

摘要:从川芎根内生真菌Peniophora incarnate中分离到一种新发现的clestan烷型二萜，命名为incarnatin A(1)。通过HRMS和NMR结合ECD计算等光谱手段明确地阐明了其绝对构型。转录组测序表明，1能抑制血管生成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Records of Natural Products 生物-医药化学

CiteScore

3.10

自引率

26.30%

发文量

审稿时长

4 months

期刊介绍： Records of Natural Products is a journal of natural product chemistry. Reviews, book reviews, research papers and short reports are considered on the substances of plants, microbes and animals. Discussions on the structure elucidation, synthesis of naturally occurring compounds and biological activity of natural compounds and plant extracts, biosynthesis of natural products and essential oils of aromatic plants as well as chemotaxonomy in the field of plants are welcomed in the journal. All published research articles in Records of Natural Products have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.