Sustained Crohn’s Disease Remission with an Exclusive Elemental and Exclusion Diet: A Case Report

IF 0.9 Q4 GASTROENTEROLOGY & HEPATOLOGY
Farhad Mehrtash
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引用次数: 0

Abstract

The incidence of inflammatory bowel diseases, such as Crohn’s disease (CD), is increasing worldwide. Despite several new therapeutics to treat CD, many patients fail to respond to their medications and inevitably face surgical resection. While genetics plays a role in CD, environmental factors are potential triggers. Recent research from the past few years suggest that pro-inflammatory foods are associated with an increased risk of CD. Some studies have shown the benefit of including exclusion diets, such as the specific carbohydrate diet (SCD) and exclusive elemental diets, to induce CD remission, but published data is limited. This case study explores how an exclusive elemental and exclusion diet helped induce clinical and biochemical remission and radiologic healing in a young adult male who had failed to achieve remission using standard medical treatment. C-reactive protein (CRP), fecal calprotectin, and magnetic resonance enterography (MRE) served as objective markers of inflammation in this study.
纯元素排异饮食持续缓解克罗恩病1例报告
炎症性肠病(如克罗恩病)的发病率在全球范围内呈上升趋势。尽管有几种新的治疗CD的方法,但许多患者对药物没有反应,不可避免地面临手术切除。虽然遗传学在CD中发挥作用,但环境因素是潜在的触发因素。过去几年的最新研究表明,促炎性食物与CD风险增加有关。一些研究表明,包括特殊碳水化合物饮食(SCD)和纯元素饮食在内的排除性饮食对诱导CD缓解有好处,但公布的数据有限。本案例研究探讨了纯元素和排除性饮食如何有助于诱导一名年轻成年男性的临床和生化缓解以及放射学愈合,该男性未能通过标准药物治疗获得缓解。C反应蛋白(CRP)、粪便钙卫蛋白和磁共振肠造影(MRE)是本研究中炎症的客观标志物。
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来源期刊
CiteScore
1.50
自引率
0.00%
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0
审稿时长
10 weeks
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