A retrospective study on clinical and epidemiological profile of nonsyndromic cleft lip and palate patients admitted in a large Comprehensive Cleft Care Centre in West Bengal, India

Nupur Saha, M. Das, Shabnam Zahir, Arnab Santra
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Abstract

Aim: The aim of this study is to observe the clinical and epidemiological profile of nonsyndromic cleft lip (CL) and/or palate patients admitted to a cleft care center in West Bengal from May 2021 to April 2022. Materials and Methods: A retrospective epidemiological study had been done by preparing a master data sheet to record the patient's data from a Comprehensive Cleft Care Centre in West Bengal. The study variables included were patient's age reporting at the hospital, type of cleft, sex distribution of patients, residential address of the parents, socioeconomic status through parents' education, occupation, and monthly income, and consanguineous marriage history of the family. Results: A total of 276 nonsyndromic cleft patients during the time period (May 2021 to April 2022) were considered. Among these, 164 were male and 112 were female patients. The mean age of patients reporting to this hospital on average was 13–18 months. CL with palate patients (62%) predominated than any other type and was mostly seen in male patients (69.59%); isolated CL (22%) cases were more in females (56.25%), whereas isolated cleft palate (16%) cases were seen more in males (62.79%); unilateral (77%) and left-sided cleft (67%) were found predominantly than bilateral cases (23%) and seen mostly in females, whereas bilateral cleft cases were more in males. Most of the patients belonged to North 24 Parganas District which is an adjacent district of Kolkata, and most of the families belonged to a low socioeconomic group, and interestingly, most of them had consanguineous marriage history (61%) with at least one generation. Conclusion: The results of this study provided that CL with palate type is more common among all types of clefts and predominantly found in males than females in West Bengal. The unilateral left-sided cleft is predominant among all other varieties. Most of the parents belonged to low socioeconomic status and are having consanguineous marriage history. We need to spread awareness among the public through ads and banners, social media, and medical free camps about the deformity of CL and/or palate and also possible preventive measures, make arrangements for free treatment among the CL and/or CL and palate population for better life of cleft patients and their parents.
对印度西孟加拉邦一家大型综合性唇腭裂护理中心收治的非综合征性唇腭裂患者的临床和流行病学资料进行回顾性研究
目的:本研究的目的是观察2021年5月至2022年4月在西孟加拉邦一家唇裂护理中心入院的非综合征性唇裂(CL)和/或腭裂患者的临床和流行病学概况。材料和方法:通过编制主数据表记录西孟加拉邦一家综合性唇腭裂护理中心的患者数据,进行了回顾性流行病学研究。研究变量包括患者在医院的报告年龄、唇裂类型、患者的性别分布、父母的居住地址、父母的教育程度、职业、月收入等社会经济地位、家庭近亲婚姻史等。结果:共考虑了276例非综合征性唇裂患者(2021年5月至2022年4月)。其中男性164例,女性112例。到该院就诊的患者平均年龄为13-18个月。腭部CL以62%居多,男性居多(69.59%);女性单纯性腭裂发生率为22%(56.25%),男性单纯性腭裂发生率为16% (62.79%);单侧(77%)和左侧(67%)唇裂的发生率高于双侧(23%),多见于女性,而双侧唇裂的发生率高于男性。大多数患者来自与加尔各答相邻的北24 Parganas区,大多数家庭属于低社会经济群体,有趣的是,大多数患者至少有一代近亲婚姻史(61%)。结论:本研究结果表明,腭裂合并腭裂在西孟加拉邦所有类型的腭裂中更为常见,男性多于女性。单侧左侧唇裂在所有其他品种中占主导地位。大多数父母属于低社会经济地位,有近亲婚姻史。我们需要通过广告、横幅、社交媒体、医疗免费营等方式向公众宣传腭裂和/或腭裂的畸形以及可能的预防措施,安排腭裂和/或腭裂人群的免费治疗,让腭裂患者及其父母过上更好的生活。
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