Are the upper bounds for new SARS-CoV-2 infections in Germany useful?

Q2 Mathematics
Wolfgang Bock, Thomas Götz, Y. Jayathunga, R. Rockenfeller
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引用次数: 2

Abstract

Abstract At the end of 2019, an outbreak of a new coronavirus, called SARS–CoV–2, was reported in China and later in other parts of the world. First infection reported in Germany by the end of January 2020 and on March 16th, 2020 the federal government announced a partial lockdown in order to mitigate the spread. Since the dynamics of new infections started to slow down, German states started to relax the confinement measures as to May 6th, 2020. As a fall back option, a limit of 50 new infections per 100,000 inhabitants within seven days was introduced for each district in Germany. If a district exceeds this limit, measures to control the spread of the virus should be taken. Based on a multi–patch SEAIRD–type model, we will simulate the effect of choosing a specific upper limit for new infections. We investigate, whether the politically motivated bound is low enough to detect new outbreaks at an early stage. Subsequently, we introduce an optimal control problem to tackle the multi–criteria problem of finding a bound for new infections that is low enough to avoid new outbreaks, which might lead to an overload of the health care system, but is large enough to curb the expected economic losses.
德国新的严重急性呼吸系统综合征冠状病毒2型感染的上限有用吗?
2019年底,一种名为SARS-CoV-2的新型冠状病毒在中国爆发,随后在世界其他地区爆发。到2020年1月底,德国报告了第一例感染病例,2020年3月16日,联邦政府宣布部分封锁,以减轻传播。由于新感染的动态开始放缓,德国各州从2020年5月6日开始放松隔离措施。作为备选方案,德国每个区在7天内每10万居民新增感染人数不得超过50人。如果一个地区超过了这个限制,就应该采取措施控制病毒的传播。基于多补丁seaird型模型,我们将模拟为新感染选择特定上限的效果。我们调查了出于政治动机的界限是否低到足以在早期发现新的疫情。随后,我们引入了一个最优控制问题来解决寻找一个足够低的新感染边界的多准则问题,以避免新的爆发,这可能导致卫生保健系统的过载,但足够大,以抑制预期的经济损失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Computational and Mathematical Biophysics
Computational and Mathematical Biophysics Mathematics-Mathematical Physics
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
30 weeks
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