Changes in blood and renal function in patients after cerebral digital subtraction angiography

Research in diagnostic and interventional imaging Pub Date : 2023-09-01 DOI:10.1016/j.redii.2023.100032

Juan Manuel Marquez-Romero , Marco Zenteno , Antonio Arauz

{"title":"Changes in blood and renal function in patients after cerebral digital subtraction angiography","authors":"Juan Manuel Marquez-Romero , Marco Zenteno , Antonio Arauz","doi":"10.1016/j.redii.2023.100032","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Describe the incidence of contrast-induced acute renal injury (CI-AKI) and the changes in hematocrit in a cohort of patients undergoing elective cerebral digital subtraction angiography (DSA).</p></div><div><h3>Methods</h3><p>In this prospective study, patients undergoing cerebral DSA were assessed for hematocrit level and CI-AKI risk factors before the procedure and for developing CI-AKI 72 h after exposure to the contrast media.</p></div><div><h3>Results</h3><p>Among 215 patients (109 men, mean age 36.6 years). The most frequently found CI-AKI risk factor was hypertension. There were no cases of permanent renal impairment after 14 days. Significant changes were observed in hematocrit (45.7 ± 4.9, vs. 44.5 ± 4.6, <em>p</em> = 0.001), estimated creatinine clearance (129.7 ± 48.3, vs. 123.1 ± 40.5, <em>p</em> = 0.002), and serum creatinine (0.72 ± 0.19, vs 0.74 ± 0.18, <em>p</em> = 0.031). The mean change in serum creatinine 72 h after contrast administration was +0.27 ± 0.10 mg/dL (<em>p</em> < 0.05).</p></div><div><h3>Conclusions</h3><p>The incidence of CI-AKI after elective cerebral DSA was 1.4%. A significant decrease in hematocrit was observed up to 72 h after the procedure.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"7 ","pages":"Article 100032"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research in diagnostic and interventional imaging","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S277265252300011X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

Describe the incidence of contrast-induced acute renal injury (CI-AKI) and the changes in hematocrit in a cohort of patients undergoing elective cerebral digital subtraction angiography (DSA).

Methods

In this prospective study, patients undergoing cerebral DSA were assessed for hematocrit level and CI-AKI risk factors before the procedure and for developing CI-AKI 72 h after exposure to the contrast media.

Results

Among 215 patients (109 men, mean age 36.6 years). The most frequently found CI-AKI risk factor was hypertension. There were no cases of permanent renal impairment after 14 days. Significant changes were observed in hematocrit (45.7 ± 4.9, vs. 44.5 ± 4.6, p = 0.001), estimated creatinine clearance (129.7 ± 48.3, vs. 123.1 ± 40.5, p = 0.002), and serum creatinine (0.72 ± 0.19, vs 0.74 ± 0.18, p = 0.031). The mean change in serum creatinine 72 h after contrast administration was +0.27 ± 0.10 mg/dL (p < 0.05).

Conclusions

The incidence of CI-AKI after elective cerebral DSA was 1.4%. A significant decrease in hematocrit was observed up to 72 h after the procedure.

查看原文本刊更多论文

脑数字减影血管造影术后患者血液和肾功能的变化

目的描述一组接受选择性脑数字减影血管造影术（DSA）的患者中造影剂诱导的急性肾损伤（CI-AKI）的发生率和红细胞压积的变化，接受脑DSA的患者在手术前评估红细胞压积水平和CI-AKI风险因素，并在暴露于造影剂72小时后评估CI-AKI。结果215例患者中男性109例，平均年龄36.6岁。最常见的CI-AKI危险因素是高血压。14天后无永久性肾功能损害病例。红细胞压积（45.7±4.9，vs.44.5±4.6，p=0.001）、估计肌酐清除率（129.7±48.3，vs.123.1±40.5，p=0.002）发生显著变化，血清肌酸酐（0.72±0.19，vs 0.74±0.18，p=0.031）。对比剂给药后72小时血清肌酸酐的平均变化为+0.27±0.10 mg/dL（p＜0.05）。结论选择性脑DSA后CI-AKI的发生率为1.4%。术后72小时血细胞比容显著下降。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Research in diagnostic and interventional imaging Radiology and Imaging

自引率

0.00%

发文量