Short Term Outcome of Goniotomy with Kahook Dual Blade in the Management of Primary Open Angle Glaucoma-A Retrospective Interventional Case Series

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Abstract

Objectives: To describe short-term efficacy of goniotomy with trabecular meshwork excision using the Kahook Dual Blade (KDB, New World Medical Inc., Rancho Cucamonga, CA) in patients with Primary Open Angle Glaucoma, (POAG) either as a standalone or plus Phacoemulsification (phaco). Method and Patients: A retrospective review of 12 eyes of 9 patients who had goniotomy with Kahook dual blade either as a standalone or combined with cataract surgery by phacoemulsification from April 2017 to July 2018 at Eye Foundation Hospital, Ikeja, Lagos. The patients were follow-up for a minimum of 6 months. Results: The mean age of the patients was 66.4±8.8 years. Mean preoperative intraocular pressure (IOP) for all eyes was 18.58±5.42mmHg. From day 1 through the 6th Month of postoperative follow-up, the mean IOP ranged from 18.58±9.26mmHg to 12.27±1.68mmHg representing reductions of 0-6.31mmHg (0-34%; p<0.05 at each time point versus baseline except for day 1). For the Phaco+KDB group, the baseline mean IOP was 19.25±4.56mmHg while the mean IOP postoperatively from day 1 to 6 months ranged from 19.13±8.99mmHg to 12.13±1.89mmHg representing reductions of 0.12mmHg to 5.13mmHg (0.6-30.2%; p<0.05 only from 1 month to 6 months). At baseline, the mean IOP for the eyes that had KDB goniotomy as a standalone was 17.25±7.45mmHg and postoperatively ranged from 17.50±11.09mmHg to 12.67±1.67mmHg representing reductions of -0.25-9.08mmHg (-1.45%-41.7%; p<0.05 at one week, 3 and 6 months only versus baseline). Conclusion: KDB either as a standalone or with phaco recorded at least 30% reduction in IOP after 6 months of followup in these series.
Kahook双刀片性腺切除术治疗原发性开角型青光眼的近期疗效——回顾性介入治疗病例系列
目的:描述使用Kahook Dual Blade(KDB,New World Medical股份有限公司,Rancho Cucamonga,CA)对原发性开角型青光眼患者进行小梁网切除的角度切开术的短期疗效,(POAG)是一种独立或联合超声乳化术(phaco)。方法和患者:2017年4月至2018年7月,在拉各斯Ikeja眼科基金会医院,对9名患者中的12只眼睛进行了回顾性审查,这些患者使用Kahook双刀片进行了单体或联合白内障超声乳化手术。患者接受了至少6个月的随访。结果:患者平均年龄为66.4±8.8岁。所有眼睛的平均术前眼压(IOP)为185.8±5.42mmHg。从术后随访的第1天到第6个月,平均IOP范围为18.58±9.26mmHg到12.27±1.68mmHg,代表0-6.31mmHg的降低(0-34%;除第1天外,每个时间点与基线相比均<0.05)。Phaco+KDB组的基线平均眼压为19.25±4.56mmHg,而术后第1天至第6个月的平均眼压范围为19.13±8.99mmHg至12.13±1.89mmHg,代表0.12mmHg至5.13mmHg的下降(0.6-30.2%;仅从1个月至6个月p<0.05)。在基线时,用阿司他龙行KDB开角术的平均眼压为17.25±7.45mmHg,术后范围为17.50±11.09mmHg至12.67±1.67mmHg,代表-0.25-9.08mmHg的下降(-1.45%-41.7%;仅在一周、3个月和6个月时与基线相比p<0.05)系列
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