Microneedling with autologous platelet-rich plasma versus topical insulin for treating postacne scars: A split-face comparison

Q3 Medicine

Journal of Cutaneous and Aesthetic Surgery Pub Date : 2023-08-04 DOI:10.4103/jcas.jcas_20_23

A. Mohta, M. Yadav, B. Ghiya

引用次数: 0

Abstract

Post-acne atrophic scars (PAS) are a common complication of acne, and their treatment can be limited in people of color due to dyspigmentation and scarring risks. This split-face study compared the efficacy of microneedling with topical insulin (TI) on one side of the face with microneedling with platelet-rich plasma (PRP) on the other side for the treatment of PAS. The study included 50 participants with Fitzpatrick skin types III to VI who had never been treated for PAS. Both sides of the face showed significant improvement, with the left side (TI) showing a 52% improvement and the right side (PRP) showing a 28% improvement. The treatment was well-tolerated, with no significant adverse effects, and no changes in blood glucose levels were observed. The researchers suggest that combining TI or PRP with microneedling can improve PAS treatment, with TI being a superior option due to its ease of use, low cost, and noninvasive nature.

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自体富血小板血浆微针与外用胰岛素治疗痤疮后疤痕:裂脸比较

痤疮后萎缩性疤痕（PAS）是痤疮的常见并发症，由于色素沉着和疤痕风险，有色人种的治疗可能受到限制。这项分面研究比较了微针和局部胰岛素（TI）在一侧脸上的疗效，以及微针和富血小板血浆（PRP）在另一侧脸上治疗PAS的疗效。该研究包括50名Fitzpatrick III至VI型皮肤的参与者，他们从未接受过PAS治疗。面部两侧均有明显改善，左侧（TI）改善52%，右侧（PRP）改善28%。该治疗耐受性良好，没有明显的不良反应，也没有观察到血糖水平的变化。研究人员认为，将TI或PRP与微针相结合可以改善PAS治疗，TI由于其易用、低成本和无创性，是一种优越的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cutaneous and Aesthetic Surgery Medicine-Surgery

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

29 weeks

期刊介绍： The journal will cover aspects of Dermatosurgery and Aesthetic surgery, including cutaneous surgical procedures, lasers, light based treatments and aesthetic treatments. Authors of articles addressing topics such as skin tumours, pigmentary disorders, histopathology, diagnostic techniques, drugs, applications of cosmeceuticals surgical aspects, including pre and post procedural care are highly encouraged to submit with us. The journal also publishes articles on topics in allied specialities suh as plastic surgery, maxillofacial surgery vascular surgery, oculoplastic surgery etc. that are relevant to Dermatosurgery. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed Original Research Articles, Systematic reviews, Narrative Reviews, Case reports, Innovations and Debates. Letters to the editor, practice points, pearls in cutaneous and aesthetic surgery, quiz page, images, novel techniques, newer uses of instruments and video presentations and ethical aspects of cutaneous and aesthetic surgery are also invited.