Antibacterial Activity of Salam (Syzygium polyanthum) Leaves 70% Ethanolic Extract on Staphylococcus aureus and Staphylococcus epidermidis

Journal of Tropical Pharmacy and Chemistry Pub Date : 2021-12-25 DOI:10.25026/jtpc.v5i4.352

Ayu Nala El Muna Haerussana, Wulan Putri Dwiastuti, Cindi Arwan Sukowati

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引用次数: 1

Abstract

Indonesia has a high diversity of potential medicinal plants, which are the second-largest number of indigenous medicinal plants in the world. Syzygium polyanthum, known as Indonesian Bay Leaf or Salam, easily found, widely used in Indonesia as a spice in cooking and traditional medicine. Salam contains secondary metabolites such as flavonoids, alkaloids, tannins, essential oils, sesquiterpenes, triterpenes, phenols, steroids, and saponins. Staphylococcus aureus and Staphylococcus epidermidis are the main bacteria that cause commensal infection and the most common nosocomial infections. This study aims to know the antibacterial activity of the Salam ethanolic extract against Staphylococcus aureusand Staphylococcus epidermidis bacteria. Salam leaves were extracted by 70% ethanol in the maceration method. Antibacterial activity was conducted by the disk diffusion method. The extract exhibits moderate activity (10.51±0.3 mm) at 75% of concentration and low activity (3.69±0.4 mm) at 100% of concentration against Staphylococcus aureus and Staphylococcus epidermidis respectively. The test showed that salam leaves extract had antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis.

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Salam（Syzygium polyanthum）叶70%乙醇提取物对金黄色葡萄球菌和表皮葡萄球菌的抗菌活性

印度尼西亚具有高度多样性的潜在药用植物，是世界上第二大本土药用植物。多花参，又名印尼月桂叶或Salam，很容易找到，在印度尼西亚广泛用作烹饪和传统医学的香料。萨拉姆含有次生代谢物，如类黄酮、生物碱、单宁、精油、倍半萜、三萜、酚类、类固醇和皂苷。金黄色葡萄球菌和表皮葡萄球菌是引起共生感染的主要细菌，也是最常见的医院感染。本研究旨在了解Salam乙醇提取物对金黄色葡萄球菌和表皮葡萄球菌的抑菌活性。用70%乙醇浸渍法提取萨拉姆叶。采用纸片扩散法测定其抑菌活性。提取物在75%浓度下对金黄色葡萄球菌和表皮葡萄球菌具有中等活性(10.51±0.3 mm)，在100%浓度下对表皮葡萄球菌具有低活性(3.69±0.4 mm)。实验结果表明，萨拉姆叶提取物对金黄色葡萄球菌和表皮葡萄球菌均有抑菌活性。

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来源期刊

Journal of Tropical Pharmacy and Chemistry

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审稿时长

6 weeks