Locally advanced cervical cancer treated with chemo-radiotherapy: a case report of a particular recurrence

Abstract

Adenocarcinoma of uterine cervix is usually treated with concurrent chemotherapy and external beam radiotherapy (EBRT), eventually followed by brachytherapy that can provide a good tumor control rate, although approximately one-third of the patients can develop further recurrence. The most common recurrence sites are the pelvis and the para-aortic nodes, with few patients having a single metastatic deposit. In this regard, precise definitions of recurrences and optimal treatment strategies are still to be clearly defined and currently there are no guidelines for the treatment of patients with oligometastatic cervical cancer. We present a case of an 81 years old patient with Stage IIB adenocarcinoma of uterine cervix, that was successfully treated with concurrent chemoradiotherapy with definitive intent. Six months later, she developed a solitary abdominal nodule for which she underwent resection followed by chemotherapy. At the present time there are no signs of local recurrence or distant metastasis after 3 years. In the case reported, the use of different strategies (radiotherapy, chemotherapy and surgery), as well as the correct choice and the timing of the different approaches has provided a great benefit for the patient. The use of surgery and chemotherapy in patients with recurrent cervical cancer is safe even in older patients with atypical