Spectrum and pattern of distribution of findings in patients with dyspepsia undergoing oesophago-gastro-duodenoscopy at a Tertiary Hospital in Ibadan, south west, Nigeria

Pub Date : 2021-01-01 DOI:10.1080/20905068.2021.1913890

Kolawole Oluseyi Akande, T. Oke, O. Afuwape, T. Adigun, A. Akere, Ajibola Aje, S. Ola, J. Otegbayo

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Abstract

ABSTRACT Introduction: Dyspepsia is a symptom complex with varied underlying etiologies. The underlying etiology determines the precise treatment and prognosis though Helicobacter pylori infection plays a central role. The aim of this study was to describe the spectrum and pattern of distribution of findings in patients with dyspepsia undergoing oesophago-gastro-duodenoscopy at the University College Hospital, Ibadan. Methods: A retrospective analysis of computerized database patients with dyspepsia who underwent oesophago-gastro–duodenoscopy from 2015 to 2019. Results: A total of 1,373 procedures were done and dyspepsia was the indication in 736 (53.2%) comprising 317 (43.1%) male and 405 (55%) female (P< .001). The age ranged from 18 to 100 with a mean of 50 ± 15 years. The age group 40–59 years had the highest representation (P = .00). The esophageal mucosa was normal in 592 (80.4%) while 45 (6.1%) and 36 (4.9%) patients had esophagitis and esophageal candidiasis, respectively. In the stomach, 230 (31%) patients had normal mucosa while 433 (57.5%) and 40 (5.4%) patients had gastritis and gastric ulcers, respectively. Antrum was the most commonly involved site by the gastritis and ulcers in 236 (55.8%) and 24 (60%) patients, respectively. The mean age of those with non-ulcer dyspepsia was 49.8 ± 15 while that of those with organic dyspepsia was 55.7 ± 13.7 years (P= .01). Furthermore, there was a significant correlation between the age group and organic dyspepsia (P = .00). The first part of the duodenum was normal in 594 (80.7%) while bulbar duodenitis was seen in 106 (14.4%). Conclusion: In our practice, OGD in patients with dyspepsia is either normal or yielded few abnormalities. The most common abnormalities were gastritis, duodenitis, esophagitis and gastric ulcers. Gastritis and ulcers were antral predominant and gastric ulcers were more common than duodenal ulcers. There was a significant relationship between increasing age and organic dyspepsia.

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在尼日利亚西南部伊巴丹的一家三级医院接受食道胃十二指肠镜检查的消化不良患者的发现频谱和分布模式

摘要简介：消化不良是一种复杂的症状，其病因多种多样。尽管幽门螺杆菌感染起着核心作用，但潜在的病因决定了确切的治疗和预后。本研究的目的是描述在伊巴丹大学学院医院接受食道胃十二指肠镜检查的消化不良患者的发现谱和分布模式。方法：对2015年至2019年接受食道胃十二指肠镜检查的消化不良计算机数据库患者进行回顾性分析。结果：共进行了1373次手术，736例（53.2%）以消化不良为指征，其中317例（43.1%）为男性，405例（55%）为女性（P<.001）。年龄从18岁到100岁，平均50±15岁。40-59岁年龄组的代表性最高（P=0.00）。592例（80.4%）食管粘膜正常，45例（6.1%）和36例（4.9%）患者分别患有食道炎和食道念珠菌感染。在胃中，230名（31%）患者粘膜正常，433名（57.5%）和40名（5.4%）患者分别患有胃炎和胃溃疡。在236例（55.8%）和24例（60%）患者中，Antrum是胃炎和溃疡最常见的受累部位。非溃疡性消化不良患者的平均年龄为49.8±15岁，而器质性消化不良者的平均年龄则为55.7±13.7岁（P=0.01）。此外，该年龄组与器质性营养不良之间存在显著相关性（P=0.00）。594例（80.7%）十二指肠第一部分正常，106例（14.4%）可见球十二指肠炎。结论：在我们的实践中，消化不良患者的OGD要么正常，要么很少出现异常。最常见的异常是胃炎、十二指肠炎、食管炎和胃溃疡。胃炎和溃疡以胃窦为主，胃溃疡比十二指肠溃疡更常见。年龄增长与器质性消化不良之间存在显著关系。

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