Assessment of Eco-genotoxic Effects of Pesticide Mixtures on Freshwater Fish, Catla catla

Q3 Pharmacology, Toxicology and Pharmaceutics

Current Trends in Biotechnology and Pharmacy Pub Date : 2020-02-22 DOI:10.5530/CTBP.2021.1.5

B. Bhargavi, R. K. Vellanki, Rajanikanth Akurathi, J. R. Kanala

引用次数: 0

Abstract

Eco-genotoxicity was evaluated in fresh water fish, Catla catla using two commercially available pesticide mixtures, viz., Deltamethrin 1% + Triazophos 35% EC and Profenofos 40% EC + Cypermethrin 4% EC. Acute toxicity studies were conducted primarily to determine LC50 of each pesticide mixture. The fish were exposed to each pesticide mixture for 21 days at a dose value of 1/ 20th and 1/10th of LC50. The gills were isolated from the fish at the end of the exposure period, and processed for comet assay. Nucleoids were scored visually, observed significant increase of damage and categorized into various degrees of damages. Based on the results obtained from this study it is concluded that the pesticide mixtures evaluated could be potentially genotoxic to fresh water fish, Catla catla.

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混合农药对淡水鱼的生态遗传毒性评价

使用两种市售农药混合物，即1%的溴氰菊酯+35%的三唑磷EC和40%的毒死蜱+4%的氯氰菊酯EC，对淡水鱼Catla Catla的生态遗传毒性进行了评估。将鱼暴露于每种杀虫剂混合物21天，剂量值分别为LC50的1/20和1/10。在暴露期结束时，从鱼身上分离出鳃，并进行彗星分析。对核苷酸进行视觉评分，观察到损伤的显著增加，并将其分为不同程度的损伤。根据这项研究的结果，可以得出结论，所评估的杀虫剂混合物可能对淡水鱼Catla Catla具有潜在的遗传毒性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Trends in Biotechnology and Pharmacy Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： The Association of Biotechnology and Pharmacy (ABAP) will be useful to form a forum for scientists so that they can bring together to discuss and find scientific solutions to the problems of society. The annual meetings will help the members to share their knowledge and publish their research knowledge particularly by members and fellows of the Association and special care will be taken to provide an opportunity for young scientists. Besides this the association is planned to organize symposia, seminars and workshops on current developments of Biotechnology and Pharmacy particularly on the subject of current scientific interest, and the proceedings of which will be published regularly. And in view of the vast development of science and to disseminate the problems in publication of research work, an international journal of Current Trends in Biotechnology and Pharmacy has been started by ABAP.