Acne Necrotica (Varioliformis) – Case Report

M. Nikolić, J. Perić, D. Škiljević
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引用次数: 2

Abstract

Abstract Acne necrotica is a rare disease, characterized by repeated cropping of inflammatory papules and papulo-pustules, which rapidly necrotize and leave varying degrees of varioliform scars that may lead to cicatricial alopecia when terminal hair-bearing sites are involved. In early lesions, pathology shows necrotizing lymphocytic folliculitis. We report a 63-year-old male patient with chronic, relapsing, umbilicated and centrally necrotic erythematous papules and papulo-pustules involving the frontal hairline area, face, and neck. Histopathology showed epidermal spongiosis and lymphocytic exocytosis, extensive necrosis and destruction of the follicular epithelium, a dense diffuse lymphohistiocytic infiltrate and necrosis of the perifolicular dermis. The diagnosis of acne necrotica was made based on the correlation of clinical and histopathological findings. A complete clinical remission was achieved with topical erythromycin and benzoyl peroxide.
坏死性痤疮(静脉曲张)- 1例报告
摘要坏死性痤疮是一种罕见的疾病,其特征是反复出现炎症性丘疹和丘疹性脓疱,这些丘疹和脓疱会迅速坏死并留下不同程度的天花状疤痕,当涉及末端毛发部位时,可能导致瘢痕性脱发。在早期病变中,病理显示坏死性淋巴细胞毛囊炎。我们报告了一名63岁的男性患者,患有慢性、复发性、脐状和中央坏死的红斑丘疹和丘疹性脓疱,累及额发际线区域、面部和颈部。组织病理学显示表皮海绵状细胞增多和淋巴细胞胞吐,毛囊上皮广泛坏死和破坏,叶周真皮致密弥漫性淋巴组织细胞浸润和坏死。坏死性痤疮的诊断是基于临床和组织病理学结果的相关性。局部使用红霉素和过氧化苯甲酰可获得完全的临床缓解。
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期刊介绍: Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.
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