INFLUENCE OF PECTIN AND CHITOSAN ON THE PROPERTIES OF GELS PROTECTING THE OESOPHAGEAL MUCOSA

IF 0.8 Q4 MATERIALS SCIENCE, BIOMATERIALS

Progress on Chemistry and Application of Chitin and its Derivatives Pub Date : 2021-09-30 DOI:10.15259/pcacd.26.014

K. Małolepsza-Jarmołowska

引用次数: 0

Abstract

Among the diseases of the digestive tract, gastro-oesophageal reflux is one of the most troublesome ailments. It is estimated that in highly developed countries, reflux symptoms occur in about 5%-10% of people every day. It has also been found that about 20% of people experience such symptoms once a week. The incidence of this disease increases with age, regardless of gender. The aim of the study was to investigate the physicochemical properties of gels intended for the protection of the oesophageal mucosa. Preparations containing 3.0% pectin showed the lowest pH. These gels can be used in the treatment of advanced alkaline reflux. The addition of chitosan to all tested gels increased their pH and dynamic viscosity. The texture tests showed the effect of pectin concentration on the adhesion work of the tested gels.

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果胶和壳聚糖对食管黏膜保护凝胶性能的影响

在消化道疾病中，胃食管反流是最令人头疼的疾病之一。据估计，在高度发达的国家，每天约有5%-10%的人出现反流症状。研究还发现，大约20%的人每周都会出现一次这种症状。这种疾病的发病率随着年龄的增长而增加，不分性别。本研究的目的是研究用于保护食道粘膜的凝胶的物理化学性质。含有3.0%果胶的制剂pH值最低。这些凝胶可用于治疗晚期碱性反流。在所有测试的凝胶中添加壳聚糖增加了它们的pH值和动态粘度。质地测试表明果胶浓度对测试凝胶的粘附功的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Progress on Chemistry and Application of Chitin and its Derivatives MATERIALS SCIENCE, BIOMATERIALS-

CiteScore

1.10

自引率

16.70%

发文量

期刊介绍： Progress in the Chemistry and Application of Chitin and its Derivatives is an annual journal focused on all aspects of production, modification, enzymology and application of chitin and its many derivatives, including chitosan. The journal publishes full-length papers as well as invited reviews. To be considered, papers must present original research that has not been published or accepted for publication elsewhere. The language of the journal will be English.