Remineralization of Dentine Caries Using Moringa Oleifera Based Nano-Silver Fluoride: A Single-Blinded, Randomized, Active-Controlled Clinical Trial

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Dental Hypotheses Pub Date : 2022-07-01 DOI:10.4103/denthyp.denthyp_57_22

Duaa J Kadhem, A. A. Al Haidar

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引用次数: 2

Abstract

Introduction: Dental caries is one of the most common chronic childhood diseases, and many decayed teeth remain untreated in underdeveloped and developing countries. This clinical trial aimed to evaluate the remineralization effect of Moringa oleifera-based nano-silver fluoride (NSF) on deciduous dentin caries Materials and Method: This study was a randomized, single-blinded clinical trial. A total of 138 teeth with carious lesions belonging to 83 children were selected and randomly assigned into three groups. Clinical evaluation was performed at 1 and 3 months after intervention. Results: The percentage of arrested caries within the groups were 86%, 42%, and 37% for NSF, MI varnish (GC, Japan), and FluoroDose varnish groups (Centrix Inc, USA), respectively. Results of 1 and 3 months follow-up period were same. Statistically significant difference was found between study groups (P < 0.001). Conclusion: The present study showed that M. oleifera-based NSF could be used for arresting dental caries when applied directly to the carious lesion.

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基于辣木的纳米氟化银治疗牙本质龋的再矿化:一项单盲、随机、主动对照的临床试验

简介:龋齿是儿童最常见的慢性疾病之一，在不发达国家和发展中国家，许多蛀牙得不到治疗。本临床试验旨在评价辣木基纳米氟化银(NSF)对乳牙本质龋的再矿化作用。材料与方法:本研究为随机、单盲临床试验。选取83例儿童138颗龋齿，随机分为3组。分别于干预后1个月和3个月进行临床评价。结果:NSF组、MI清漆组(日本GC公司)和FluoroDose清漆组(美国Centrix公司)的龋率分别为86%、42%和37%。随访1个月与3个月结果相同。研究组间差异有统计学意义(P < 0.001)。结论:油橄榄基NSF直接应用于龋损处，具有抑制龋病的作用。

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