A mathematical model to study the spread of COVID-19 and its control in India

Q2 Mathematics
R. Naresh, S. Sundar, S. Verma, J. B. Shukla
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Abstract

Abstract In this article, a nonlinear mathematical model is proposed and analyzed to study the spread of coronavirus disease (COVID-19) and its control. Due to sudden emergence of a peculiar kind of infection, no vaccines were available, and therefore, the nonpharmaceutical interventions such as lockdown, isolation, and hospitalization were imposed to stop spreading of the infectious disease. The proposed model consists of six dependent variables, namely, susceptible population, infective population, isolated susceptible population who are aware of the undesirable consequences of the COVID-19, quarantined population of known infectives (symptomatic), recovered class, and the coronavirus population. The model exhibits two equilibria namely, the COVID-19-free equilibrium and the COVID-19-endemic equilibrium. It is observed that if basic reproduction number R 0 < 1 {R}_{0}\lt 1 , then the COVID-19-free equilibrium is locally asymptotically stable. However, the endemic equilibrium is locally as well as nonlinearly asymptotically stable under certain conditions if R 0 > 1 {R}_{0}\gt 1 . Model analysis shows that if safety measures are adopted by way of isolation of susceptibles and quarantine of infectives, the spread of COVID-19 disease can be kept under control.
研究COVID-19在印度传播及其控制的数学模型
摘要本文提出并分析了一个非线性数学模型,以研究冠状病毒疾病(新冠肺炎)的传播及其控制。由于一种特殊感染的突然出现,没有疫苗可用,因此,采取了封锁、隔离和住院等非药物干预措施来阻止传染病的传播。所提出的模型由六个因变量组成,即易感人群、感染人群、意识到新冠肺炎不良后果的隔离易感群体、已知感染者的隔离人群(有症状)、康复人群和冠状病毒人群。该模型表现出两种平衡,即无新冠肺炎平衡和有新冠肺炎的平衡。可以观察到,如果基本再现数R0<1{R}_{0}\lt 1,则无COVID-19的平衡是局部渐近稳定的。然而,当R0>1时,地方性平衡在一定条件下是局部和非线性渐近稳定的{R}_{0}\gt 1。模型分析表明,如果采取隔离易感人群和隔离传染源的安全措施,新冠肺炎的传播可以得到控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Computational and Mathematical Biophysics
Computational and Mathematical Biophysics Mathematics-Mathematical Physics
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
30 weeks
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