FEATURES OF THE DEVELOPMENT AND HEALTH CONDITION OF CHILDREN CONCEIVED BY IN VITRO FERTILIZATION

IF 0.6
Nailya R. Pimenova, E. Kashirskaya, N.P. Provatar, E. Novikova, N. Tkacheva, Aleksey Zhidovinov, L. Goncharova
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Abstract

Aim: To study the anamnesis, development parameters and health condition in the first year of life of the children conceived by IVF. Materials and Methods: 116 children born by IVF and 46 children born in natural pregnancy were examined. Results: In most cases of our study, children after IVF were born prematurely from women with a bad obstetric and gynecological history and had a low birth weight. The period of early adaptation in premature infants born after assisted reproductive technologies was complicated by respiratory distress syndrome. Most often the children after IVF had such pathologies as central nervous system damage, deficiency anemia and minor anomalies of heart development in the neonatal period. Compared with children born in natural pregnancy, infectious diseases were more often detected in newborns after IVF. The development of bronchopulmonary dysplasia was significantly more frequent in children after IVF within a month of life. At six months, most of the IVF babies had low parameters of physical development, whereas weight and growth indicators did not differ significantly from the general population indicators by the first year of life. Most of the children born after IVF had neurological outcomes, such as delayed psychomotor development, malfunctioning of the autonomic nervous system, convulsive syndrome by the year of life. Conclusion: Children born after IVF have features of somatic status, neuropsychiatric and physical development, which indicates the need for targeted monitoring and continued research in this group of children to minimize health risks.
体外受精儿童的发育特点及健康状况
目的:了解体外受精(IVF)患儿出生后第一年的记忆、发育参数及健康状况。材料与方法:对116例试管婴儿出生的儿童和46例自然妊娠出生的儿童进行检查。结果:在我们研究的大多数病例中,试管婴儿后的孩子是由有不良产科和妇科病史且出生体重较低的女性早产的。辅助生殖技术后出生的早产儿的早期适应期因呼吸窘迫综合征而复杂。试管婴儿后的儿童在新生儿期通常会出现中枢神经系统损伤、缺乏性贫血和轻微的心脏发育异常等疾病。与自然妊娠期出生的儿童相比,试管婴儿后的新生儿更容易发现感染性疾病。体外受精后一个月内,儿童支气管肺发育不良的发生率明显更高。在六个月大的时候,大多数试管婴儿的身体发育参数都很低,而到出生第一年,体重和生长指标与一般人群指标没有显著差异。大多数试管婴儿后出生的孩子在出生时都会出现神经系统疾病,如精神运动发育迟缓、自主神经系统功能紊乱、抽搐综合征。结论:试管婴儿后出生的儿童具有身体状态、神经精神和身体发育的特点,这表明需要对这一群体儿童进行有针对性的监测和持续研究,以最大限度地降低健康风险。
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来源期刊
Archiv EuroMedica
Archiv EuroMedica MEDICINE, GENERAL & INTERNAL-
自引率
83.30%
发文量
140
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