Prevalence of Dyslipidemia among Women with Polycystic Ovary Syndrome Based on Body Mass Index

Abstract

The purpose of this study was to detect the prevalence of dyslipidemia among polycystic ovary syndrome (PCOS) women with different BMIs. Study design: We conducted a cross-sectional study whereby one hundred and fifteen women diagnosed with PCOS were recruited from a fertility clinic in a 6-month period. All participants had their weight and height measured and body mass index (BMI) calculated. Thereafter, they were divided into two groups: normal BMI (BMI ≤25 kg/m2) and high BMI (BMI >25 kg/m2). Fasting blood samples were obtained and total cholesterol, triglycerides, LDL-C, HDL-C, glucose, and insulin levels were measured in both groups. Insulin resistance was calculated using the homeostasis model assessment of insulin resistance (HOMA-IR) equation. Differences in these variables were assessed using the Chi-square test and Fisher’s exact test. Results: No statistically significant differences were found between both groups of women in terms of total cholesterol, triglycerides, LDL-C, and HDL-C levels. Insulin resistance was significantly more prevalent in the high BMI (78.3%) than in the normal BMI group (59.1%) (P < 0.05). Conclusions: Dyslipidemia in women with PCOS is not related to their BMI. Early detection and treatment of dyslipidemia in this group of women will protect them from cardiovascular diseases.