Case of New Onset Acute Leukemia Complicated by Renal Calculi and Gout Attack: A Case Report

Cima Hamieh, M. El-Hussein, Elie Zaghrini
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Abstract

Increased level of uric acid could be due to several etiologies, mainly non-balanced diet, and if uncontrolled can cause serious outcomes. Hyperuricemia’s major adverse effects in an individual can include nephropathy, nephrolithiasis and uric acid depositions in joints. On the other hand, hyperuricemia can be the result of several underlying disorders, of which are the hematologic malignancies. A case presented to our institution with generalized fatigue found to have multiple electrolytes abnormalities. On further investigation, the patient was diagnosed with acute leukemia, hyperuricemia and kidney calculus and acute gouty arthritis concurrently, and treated with surgery, corticosteroid and uric acid lowering agents and pain management. Diagnosis and rapid management of acute leukemia associated with hyperuricemia is crucial to avoid the complication of uric acid accumulation in different body organs. World J Nephrol Urol. 2021;10(1):18-20 doi: https://doi.org/10.14740/wjnu424
新发急性白血病并发肾结石和痛风发作1例报告
尿酸水平升高可能是由几种病因引起的,主要是饮食不均衡,如果不加以控制,可能会导致严重后果。高尿酸血症对个体的主要不良影响包括肾病、肾结石和关节尿酸沉积。另一方面,高尿酸血症可能是几种潜在疾病的结果,其中包括血液系统恶性肿瘤。向我们机构提交的一例全身性疲劳病例发现有多种电解质异常。经进一步调查,该患者被诊断为急性白血病、高尿酸血症、肾结石和急性痛风性关节炎,并接受了手术、皮质类固醇和降尿酸药物以及疼痛管理。急性白血病合并高尿酸血症的诊断和快速治疗对于避免尿酸在不同身体器官积聚的并发症至关重要。世界肾脏泌尿学杂志。2021年;10(1):18-20 doi:https://doi.org/10.14740/wjnu424
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