Three novel Gemini amide amphiphilics synthesis, characterization, thermodynamics, surface properties and biological activity

Abstract

Three Gemini amphiphiles had prepared through reaction of amide of succinic acid with different bromo olefins. Their chemical structure was emphasized different spectroscopic methods. the surface tension measurements were investigated at 20, 40 and 60 °C. The Gemini surfactant with the longest tail clarified enhancement of surface parameters values with elevating mixture temperature.

Both (ΔG^o_ads) & (ΔG^o_mic) data are negative, providing spontaneously occurrence of adsorption and micellization processes while the positivity of (ΔS^o_ads) &(ΔS^o_mic) revealing more order for both processes. Thermodynamic behaviour increases by raising chain length. All of fabricated amphiphiles exhibited antimicrobial activity against bacteria and fungi.