MOG antibody-related disorder associated with peripheral facial nerve palsy

Q4 Immunology and Microbiology
Yuto Morishima, Akane Satake, Takanori Hata, Kishin Koh, Takamura Nagasaka, Toshiyuki Takahashi, Kazumasa Shindo, Yoshihisa Takiyama
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引用次数: 0

Abstract

A 44-year-old Japanese woman exhibited neurological symptoms including unsteadiness of gait, headache, hypoesthesia of the left face, and left-sided peripheral facial nerve palsy. Brain magnetic resonance imaging (MRI) revealed abnormal intensities in the hemispheres, brainstem, and corpus callosum. Although routine blood and cerebrospinal fluid studies were unremarkable, serum anti-myelin oligodendrocyte glycoprotein (MOG) antibody was positive. With two-time intravenous methylprednisolone pulse therapy, her symptoms gradually improved. We report here a rare case of a MOG antibody-related disorder with peripheral facial nerve palsy as a predominant symptom. We should be aware of this disease even in a case of peripheral facial nerve palsy.

与周围面神经麻痹相关的MOG抗体相关疾病
一名44岁的日本女性表现出神经系统症状,包括步态不稳、头痛、左脸感觉减退和左侧周围面神经麻痹。脑磁共振成像(MRI)显示在半球,脑干和胼胝体异常强度。虽然血常规和脑脊液检查无显著差异,但血清抗髓鞘少突胶质细胞糖蛋白(MOG)抗体呈阳性。经2次静脉注射甲基强的松龙脉冲治疗,患者症状逐渐好转。我们在此报告一例罕见的MOG抗体相关疾病,以周围面神经麻痹为主要症状。即使是周围面神经麻痹,我们也要注意这种疾病。
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来源期刊
Clinical and Experimental Neuroimmunology
Clinical and Experimental Neuroimmunology Immunology and Microbiology-Immunology and Microbiology (miscellaneous)
CiteScore
1.60
自引率
0.00%
发文量
52
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