Misoprostol rectal u oxitocina intramuscular en el manejo de la tercera fase del parto

Perinatologia y Reproduccion Humana Pub Date : 2017-06-01 DOI:10.1016/j.rprh.2017.10.005

A. Pérez-Rumbos , E. Reyna-Villasmil , N. Reyna-Villasmil , M. Rondón-Tapía

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引用次数: 0

Abstract

Objective

To compare the effectiveness of rectal misoprostol with intramuscular oxytocin in the management of the third phase of labour.

Materials and method

Patients to be treated with rectal misoprostol (group A) or intramuscular oxytocin (group B) were selected and randomised to attend delivery at the Central Hospital ‘Dr. Urquinaona’, Maracaibo, Venezuela. An evaluation was made of the general characteristics, changes in haemoglobin and haematocrit values, post-partum blood loss, and adverse effects.

Results

Complete data were obtained from 392 patients (195 from Group A and 197 from Group B), who were included in the final analysis. No significant differences were found between the groups with respect to the general characteristics (P = ns). No statistically significant differences were found in the mean values of haemoglobin and pre- and post-partum haematocrit (P = ns). There was a significant decrease in the duration of the third phase of labour in Group A compared to patients in Group B (P < .001). The estimated blood loss in patients in Group A was significantly lower (P < .05). It was observed that the patients in Group A had a tendency to a lower use of additional uterotonics (P < .05). Patients in Group A presented with a higher frequency of headache and shivering compared to patients in Group B (P < .05).

Conclusions

Misoprostol administered rectally is effective in minimising blood loss and duration of the third phase of labour.

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直肠米索前列醇或肌肉注射催产素在第三阶段分娩中的应用

目的比较直肠米索前列醇与肌注催产素在分娩第三期的疗效。材料和方法选择经直肠米索前列醇(A组)或肌注催产素(B组)治疗的患者，随机分配到中心医院Dr。乌奎那纳，马拉开波，委内瑞拉评估一般特征，血红蛋白和红细胞压积值的变化，产后失血和不良反应。结果392例患者(A组195例，B组197例)获得完整资料，纳入最终分析。在一般特征方面，两组间无显著差异(P = ns)。血红蛋白和产前、产后红细胞压积的平均值差异无统计学意义(P = ns)。与B组患者相比，a组第三产程持续时间显著缩短(P <措施)。A组患者的估计失血量显著降低(P <. 05)。观察到，A组患者有较少使用额外子宫强张剂的趋势(P <. 05)。与B组患者相比，A组患者出现头痛和寒战的频率更高(P <. 05)。结论直肠给药米索前列醇能有效减少产程第三期出血量和缩短产程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Perinatologia y Reproduccion Humana

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： Perinatología y Reproducción Humana is the official journal of the Instituto Nacional de Perinatología, Mexico. It is aimed at physicians of the area of perinatal and reproductive health (obstetrics and gynecology, maternal and fetal medicine, pediatricians, neonatologists, endocrinologists, infectious disease specialists, and neurologists) and also at health sciences professionals involved in the study of reproduction perinatal and reproductive health (chemists, biologists and neuro-physiologists). It is an electronic biannual journal, that publishes peer-reviewed original articles, in-deep reviews, letters to the editor and special sections related to basic, epidemiological, surgical, and clinical aspects in the area of perinatal and reproductive health, in English or Spanish languages and open access.