Excimer laser atherectomy combined with drug-eluting balloon for lower limb arteriosclerosis obliterans

Abstract

Objective To evaluate the efficacy of excimer laser atherectomy (ELA) combined with drug-coated balloon (DCB) in the treatment of lower limb arteriosclerosis obliterans. Methods From Sep 2016 to Dec 2018 42 patients (42 limbs) underwent ELA combined with DCB therapy. Results There were 27 males and 15 females.The mean age was (65.7±9.7) years. The average lesion length was (14.3±7.5) cm. The technical success rate was 100% and the remission rate of clinical symptoms was 92.9%. Ankle-brachial index was significantly improved from (0.45±0.15) pre-operation to (0.85±0.13) post-operation (P=0.001). The mean follow-up was 10.9 months. At 3, 6, and 12 months follow-up, the primary patency rate was 95.2%, 92.8% and 84.9%. The 1-year limb salvage rate was 95.2%. Conclusion ELA combined with DCB has a good 1-year results as our data reveal. Key words: Laser, excimer; Arteriosclerosis obliterans; Atherectomy; Drug-coated balloon; Angioplasty