Vía catecolaminérgica antiinflamatoria en pulpa dental y su relación con el control del dolor durante el manejo complementario con electroacupuntura: un estudio de cohorte

Q4 Medicine

Revista Internacional de Acupuntura Pub Date : 2023-04-01 DOI:10.1016/j.acu.2023.100250

María Eugenia Marcela Castro-Gutiérrez , Liliana Argueta-Figueroa , Mario Alberto Bautista-Hernández , Adriana Moreno-Rodríguez , Carlos Josué Solórzano-Mata , Rafael Torres-Rosas

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引用次数: 0

Abstract

Acupuncture can control inflammation and pain by modulating various neuroimmunological communication pathways, including a catecholamine-dependent pathway. On the other hand, it has been reported that there are nerve terminals of the sympathetic nervous system in the dental pulp and these nerves can control the blood flow in the dental pulp. This study aimed to determine if acupuncture has an analgesic effect on the dental pulp and the relationship with neuroimmunological control elements in this tissue. A prospective cohort study was carried out with patients scheduled for tooth extraction for orthodontic reasons, which were treated with complementary management of electroacupuncture during the extraction process (n = 17). The success of dental anesthesia was determined using electrical tests and postoperative pain scales. In addition, the presence of the α2 adrenergic receptor in cells of immune lineage in dental pulp was determined by fluorescence microscopy. The results showed that complementary therapy with electroacupuncture has a success rate of 72.5%. In addition, cells of immune lineage in dental pulp expressed α2 adrenergic receptors. Consequently, the anatomical and molecular elements in the dental pulp related to catecholaminergic neuroimmune control are present. These anatomical and molecular elements may be related to pulp anesthesia and pain control during tooth extraction.

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牙髓儿茶酚胺能抗炎途径及其与电针辅助治疗疼痛控制的关系:一项队列研究

针刺可以通过调节多种神经免疫通讯通路，包括儿茶酚胺依赖通路，来控制炎症和疼痛。另一方面，据报道，在牙髓中存在交感神经系统的神经末梢，这些神经可以控制牙髓内的血流。本研究旨在确定针灸是否对牙髓有镇痛作用，以及与牙髓组织中神经免疫控制因子的关系。一项前瞻性队列研究对因正畸原因计划拔牙的患者进行了研究，这些患者在拔牙过程中采用电针辅助治疗(n = 17)。通过电试验和术后疼痛量表来确定牙麻醉的成功与否。荧光显微镜检测牙髓免疫系细胞α2肾上腺素能受体的表达。结果表明，电针辅助治疗的成功率为72.5%。此外，牙髓免疫系细胞表达α2肾上腺素能受体。因此，牙髓中与儿茶酚胺能神经免疫控制相关的解剖和分子元素存在。这些解剖和分子因素可能与拔牙过程中的牙髓麻醉和疼痛控制有关。

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来源期刊

Revista Internacional de Acupuntura Medicine-Complementary and Alternative Medicine

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

85 days

期刊介绍： La primera revista científica en español que permite estar al día sobre avances en terapias no convencionales, favoreciendo la renovación crítica y constante de los conocimientos ya adquiridos. Cuenta con los prestigiosos contenidos de la Deustche Zeitschrift f?r Akupunktur (DZA) alemana y artículos nacionales