Successful Treatment of COVID-19-Related Immune- Complex Glomerulonephritis, Case Report.

IF 0.8 4区医学 Q4 UROLOGY & NEPHROLOGY

Iranian journal of kidney diseases Pub Date : 2022-03-01 DOI:10.52547/ijkd.6527

R. Danis, Emrah Gunay, Enver Yuksel, Ş. Kaya, Jehat Kılıç, Emrah Kacar, Ayhan Senol, Derya Deniz Altıntaş, M. S. Yıldırım

{"title":"Successful Treatment of COVID-19-Related Immune- Complex Glomerulonephritis, Case Report.","authors":"R. Danis, Emrah Gunay, Enver Yuksel, Ş. Kaya, Jehat Kılıç, Emrah Kacar, Ayhan Senol, Derya Deniz Altıntaş, M. S. Yıldırım","doi":"10.52547/ijkd.6527","DOIUrl":null,"url":null,"abstract":"Acute kidney injury (AKI) , proteinuria in the nephrotic or subnephrotic range and hematuria might be seen in patients with coronavirus disease 2019 (COVID-19) infection. In this case study we present a 59 years old manwho was diagnosed with immune-complex glomerulonephritis after development of rapidly progressive kidney failure accompanied by pulmonary hemorrhage, 2 months after COVID-19 infection. The patient was hospitalised with the diagnosis of acute kidney injury and nephrotic syndrome. Hemodialysis was performed due to uremic symptoms. Cyclophosphamide, methylprednisolone and plasmapheresis were started. Pathologic examination of kidney biopsy revealed features compatible with immune complex-related acute glomerulonephritis. Cyclophosphamide and plasmapheresis were discontinued , and treatment with 1 mg/kg/day methylprednisolone was continued. Immune-complex glomerulonephritis can be seen following COVID-19 infection. İt is important to diagnose this disease entity as soon as possible . Steroidtherapy and other supportive modalities might be sufficient in the treatment. DOI: 10.52547/ijkd.6527.","PeriodicalId":14610,"journal":{"name":"Iranian journal of kidney diseases","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian journal of kidney diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.52547/ijkd.6527","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 1

Abstract

Acute kidney injury (AKI) , proteinuria in the nephrotic or subnephrotic range and hematuria might be seen in patients with coronavirus disease 2019 (COVID-19) infection. In this case study we present a 59 years old manwho was diagnosed with immune-complex glomerulonephritis after development of rapidly progressive kidney failure accompanied by pulmonary hemorrhage, 2 months after COVID-19 infection. The patient was hospitalised with the diagnosis of acute kidney injury and nephrotic syndrome. Hemodialysis was performed due to uremic symptoms. Cyclophosphamide, methylprednisolone and plasmapheresis were started. Pathologic examination of kidney biopsy revealed features compatible with immune complex-related acute glomerulonephritis. Cyclophosphamide and plasmapheresis were discontinued , and treatment with 1 mg/kg/day methylprednisolone was continued. Immune-complex glomerulonephritis can be seen following COVID-19 infection. İt is important to diagnose this disease entity as soon as possible . Steroidtherapy and other supportive modalities might be sufficient in the treatment. DOI: 10.52547/ijkd.6527.

查看原文本刊更多论文

COVID-19相关免疫复合性肾小球肾炎的成功治疗，病例报告。

2019冠状病毒病(COVID-19)感染患者可能出现急性肾损伤(AKI)、肾病或亚肾病范围的蛋白尿和血尿。在本病例研究中，我们报告了一名59岁的男性，在COVID-19感染2个月后出现快速进展性肾衰竭并肺出血，被诊断为免疫复合物肾小球肾炎。该患者因诊断为急性肾损伤和肾病综合征而住院。因尿毒症症状行血液透析。开始使用环磷酰胺、甲基强的松龙和血浆置换。肾活检病理检查显示符合免疫复合物相关性急性肾小球肾炎的特征。停用环磷酰胺和血浆置换，继续使用1mg /kg/天的甲基强的松龙治疗。COVID-19感染后可见免疫复合物肾小球肾炎。İt是重要的诊断这种疾病实体尽快。类固醇治疗和其他支持方式可能足以治疗。DOI: 10.52547 / ijkd.6527。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Iranian journal of kidney diseases UROLOGY & NEPHROLOGY-

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.