Study of Gastro-Oesophageal Reflux Disease among Patients with Type 2 Diabetes Mellitus presenting to Medicine Department at a Tertiary Care Hospital: A Descriptive Cross-sectional Study

A. K. Mahato, Madhu Shah, Nischal Shrestha
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Abstract

Introduction: Gastro-oesophageal reflux disease is a chronic condition in which stomach contents regurgitates up into oesophagus causing symptoms like acidic taste in mouth, heart burn, bad breath and chronic cough. There is high prevalence of GERD in patients with Type 2 diabetes mellitus in the western countries, but such related data in our country are just few. Objectives: To find out the prevalence of gastroesophageal reflux among patients with Type 2 Diabetes Mellitus attending Nobel Medical College Teaching Hospital. Methodology: This was a descriptive cross-sectional study carried out in Department of Medicine of a tertiary care hospital from July 2020 to June 2021. Ethical approval was taken from Institutional Review Committee of Nobel Medical College Teaching Hospital (Reference number: 464/2020). Convenience sampling was done and data was collected from 191 patients presenting to the department. Collected data was entered, analysed in Statistical Package for the Social Sciences version 21 and documented for study. Point estimate at 95% Confidence Interval and descriptive statistics were interpreted as frequency, percentage, or as mean and standard deviations. Results: Among 191 patients with type 2 diabetes, gastroesophageal reflux was seen in 78 (40.84%) (33.87-47.81 at 95% Confidence Interval) with more prevalent in male 42 (53.84%) than female 36 (46.15%). Mean duration of type 2 diabetes among reflux cases was 10.20± 5.40 years. Conclusions: Gastroesophageal reflux was common associated condition among Diabetic patients.
某三级医院内科就诊的2型糖尿病患者胃食管反流病的研究:一项描述性横断面研究
胃食管反流病是一种慢性疾病,胃内容物反流到食道,引起口腔酸味、心脏灼热、口臭和慢性咳嗽等症状。西方国家2型糖尿病患者胃食管反流发生率较高,而我国相关资料较少。目的:了解诺贝尔医学院附属医院2型糖尿病患者胃食管反流的患病率。方法:这是一项描述性横断面研究,于2020年7月至2021年6月在一家三级医院的医学部进行。伦理批准采用诺贝尔医学院教学医院机构审查委员会(参考编号:464/2020)。对191例就诊的患者进行了方便抽样和数据收集。收集到的数据被输入,在社会科学统计包第21版中进行分析,并记录下来供研究。95%置信区间的点估计和描述性统计被解释为频率、百分比或平均值和标准差。结果:191例2型糖尿病患者中有78例(40.84%)出现胃食管反流(95%可信区间33.87 ~ 47.81),其中男性42例(53.84%)高于女性36例(46.15%)。反流患者的平均2型糖尿病病程为10.20±5.40年。结论:胃食管反流是糖尿病患者常见的相关疾病。
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