Epidemiology and prognostic factors of infantile malignant solid tumor

Q4 Medicine

中华实用儿科临床杂志 Pub Date : 2020-03-19 DOI:10.3760/CMA.J.CN101070-20200301-00298

X. Yuan

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引用次数: 0

Abstract

As an important part of childhood tumors, infantile malignant solid tumor is relatively rare, which has some common characteristics of childhood cancer as well as its own particularity.Most infantile tumors are embryo-derived tumors, whose pathogenesis is related to developmental biology, genetics and environmental factors.The distribution of constituent ratio of infantile malignant tumors is different from that of older children, and the epidemiological data statistics can be influenced by the imperfect children tumor registration system, population migration, birth defects and perinatal factors, environmental exposure, gender, race and other factors.Heterogeneity is one of the prominent features of malignant solid tumor in infants. The experience gained from treatment of older children cannot be directly extrapolated to infants.The principle of treating infantile malignant solid tumors should take into account both the effectiveness and the long-term impact on infant growth.Early diagnosis and appropriate treatment mean that the prognosis of most infants with malignant solid tumor to be better than that of older children.Therefore, it is necessary to manage these tumors as a separate entity.The advance of epidemiology and prognostic factors of infantile malignant solid tumors at home and abroad was reviewed in this paper. Key words: Infant; Malignant; Solid tumor; Incidence rate; Constituent ratio; Prognosis

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婴幼儿恶性实体瘤的流行病学及预后因素

婴幼儿恶性实体瘤作为儿童肿瘤的重要组成部分，相对罕见，既有儿童癌症的一些共同特点，也有其自身的特殊性。大多数婴儿肿瘤是胚胎源性肿瘤，其发病机制与发育生物学、遗传学和环境因素有关。婴儿恶性肿瘤的构成比分布与年龄较大的儿童不同，流行病学数据统计可能受到儿童肿瘤登记制度不完善、人口迁移、出生缺陷和围产期因素、环境暴露、性别、种族等因素的影响。异质性是婴儿恶性实体瘤的突出特征之一。从治疗年龄较大儿童中获得的经验不能直接外推到婴儿身上。治疗婴儿恶性实体瘤的原则应考虑其有效性和对婴儿生长的长期影响。早期诊断和适当治疗意味着大多数患有恶性实体瘤的婴儿的预后要好于年龄较大的儿童。因此，有必要将这些肿瘤作为一个单独的实体进行管理。本文综述了国内外婴幼儿恶性实体瘤流行病学及预后因素的研究进展。关键词：婴儿；恶性；实体瘤；发病率；成分比例；预后

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来源期刊

中华实用儿科临床杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

14243

期刊介绍： Chinese Journal of Applied Clinical Pediatrics ( semi-monthly ) is a core journal of paediatrics under the supervision of China Association for Science and Technology, sponsored by Chinese Medical Association and undertaken by Xinxiang Medical College. Founded in 1986, it is openly circulated both at home and abroad. The journal has several columns, such as Expert Forum, Experimental Research and Paediatric Surgery, which are mainly for paediatric medical workers and medical researchers in hospitals. Its purpose is to reflect the new theories and technologies in paediatric medicine and scientific research at home and abroad, and to promote academic exchanges. Chinese Journal of Applied Clinical Pediatrics is a source journal of China Science Citation Database (CSCD), a core journal of Peking University, a source journal of Chinese science and technology paper statistics (China Science and Technology Core Journals), a core academic journal of RCCSE, a high-quality scientific and technical journal of China, a high-quality scientific and technical journal of China Association for Science and Technology, and a high-quality scientific and technical journal of China Biomedical Science and Technology Association. We have been published in China Biomedical Literature Database (SinoMed), China Knowledge Network, Wanfang Data Knowledge Service Platform, China Academic Journal Abstracts, Scopus Database, Chemical Abstracts (USA), Japan Science and Technology Agency (JSTA) Database, Copernicus Abstracts (Poland), Abstracts of the Centre for Agricultural and Biological Sciences (CABS) of the United Kingdom, Cambridge Scientific Abstracts ProQuest Database, WHO Medical Journal of the Western Pacific Region (WMPR), and WHO Medical Journal of the Western Pacific Region (WMPR) of the United States. We have been included in dozens of authoritative databases at home and abroad, such as WHO Western Pacific Region Index of Medicine (WPRIM), Ullrich's Guide to Periodicals, and so on.