Disentangling the Influence of Data Contamination in Growth Curve Modeling: A Median Based Bayesian Approach

Tonghao Zhang, Xin Tong, Jianhui Zhou
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Abstract

Growth curve models (GCMs), with their ability to directly investigate within-subject change over time and between-subject differences in change for longitudinal data, are widely used in social and behavioral sciences. While GCMs are typically studied with the normal distribution assumption, empirical data often violate the normality assumption in applications. Failure to account for the deviation from normality in data distribution may lead to unreliable model estimation and misleading statistical inferences. A robust GCM based on conditional medians was recently proposed and outperformed traditional growth curve modeling when outliers are present resulting in nonnormality. However, this robust approach was shown to perform less satisfactorily when leverage observations existed. In this work, we propose a robust double medians growth curve modeling approach (DOME GCM) to thoroughly disentangle the influence of data contamination on model estimation and inferences, where two conditional medians are employed for the distributions of the within-subject measurement errors and of random effects, respectively. Model estimation and inferences are conducted in the Bayesian framework, and Laplace distributions are used to convert the optimization problem of median estimation into a problem of obtaining the maximum likelihood estimator for a transformed model. A Monte Carlo simulation study has been conducted to evaluate the numerical performance of the proposed approach, and showed that the proposed approach yields more accurate and efficient parameter estimates when data contain outliers or leverage observations. The application of the developed robust approach is illustrated using a real dataset from the Virginia Cognitive Aging Project to study the change of memory ability.
分解生长曲线建模中数据污染的影响:一种基于中位数的贝叶斯方法
生长曲线模型(Growth curve models, GCMs)具有直接研究受试者内部随时间变化和受试者之间纵向数据变化差异的能力,在社会科学和行为科学中得到广泛应用。虽然gcm通常采用正态分布假设进行研究,但在实际应用中,经验数据经常违反正态分布假设。不考虑数据分布偏离正态可能导致不可靠的模型估计和误导性的统计推断。最近提出了一种基于条件中位数的鲁棒GCM,当存在异常值导致非正态性时,它优于传统的增长曲线模型。然而,当杠杆观测存在时,这种稳健的方法表现得不太令人满意。在这项工作中,我们提出了一种稳健的双中位数增长曲线建模方法(DOME GCM),以彻底摆脱数据污染对模型估计和推论的影响,其中两个条件中位数分别用于受试者内测量误差和随机效应的分布。在贝叶斯框架下进行模型估计和推理,利用拉普拉斯分布将中值估计的优化问题转化为对变换后的模型求最大似然估计量的问题。通过蒙特卡罗模拟研究来评估所提出方法的数值性能,结果表明,当数据包含异常值或利用观测值时,所提出的方法产生更准确和有效的参数估计。利用弗吉尼亚认知衰老项目的真实数据集来研究记忆能力的变化,说明了所开发的鲁棒方法的应用。
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