Prevalence of wasting and its predictors among adults receiving highly active antiretroviral therapy in ART clinics of Hosanna town, Hadiya Zone, Southern Ethiopia A cross-sectional study

M. Asfaw, Tariku Eshetu, Fanos Yonas
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引用次数: 1

Abstract

In patients with HIV infection, wasting has been associated with increased mortality. Even in the era of Highly Active Antiretroviral Therapy (HAART), accelerated disease progression, loss of muscle protein mass, and impairment of strength and functional status are common. However, data on the magnitude of wasting and its risk factors among individuals receiving HAART are scarce in Ethiopia. The aim of this study is to determine the magnitude of wasting and identify associated factors among adults on HAART at anti-retroviral therapy clinics of Hosanna town. Facility based cross-sectional study was conducted from March 20 to April 30, 2014 among 410 adult people on (HAART) at ART health clinics of Hosanna town. Sample clients were selected by simple random sampling technique. Data were collected by face to face, record review using check list and weight scale measurement. Descriptive statistics, Bi-variate and multivariable logistic regression models were done using SPSS version 16 to identify factors associated with wasting. In total, 410 adult people on HAART participated in the study giving a response rate of 97.56%. The overall magnitude of wasting in this study was 37.1%. Food insecurity (AOR= 2.1, 95% CI: 1.28- 3.34), inadequate diversified diet (AOR= 2, 95% CI: 1.18- 3.38), low meal frequency (AOR= 2.2, 95% CI: 1.1- 4.47) and presence of opportunistic infections (AOR= 2.27, 95% CI: 1.47- 3.49) were independent predictors of wasting. Wasting was found to be high (37.1%) among adults on anti-retroviral therapy at ART Clinics of Hossana town. ART intervention should be supported by strategies that can address household food security, nutritional practices and prevention and control of opportunistic infections to improve the health status of people on HAART. Key words: Anti-retroviral therapy, HIV/AIDs, wasting, weight loss, Hosanna, town clinic.
埃塞俄比亚南部哈迪亚区Hosanna镇ART诊所接受高活性抗逆转录病毒治疗的成年人消瘦患病率及其预测因素的横断面研究
在感染艾滋病毒的患者中,消瘦与死亡率增加有关。即使在高活性抗逆转录病毒疗法(HAART)时代,疾病进展加速、肌肉蛋白质质量损失以及力量和功能状态受损也很常见。然而,在埃塞俄比亚,关于接受HAART的个人浪费程度及其风险因素的数据很少。本研究的目的是确定在Hosanna镇抗逆转录病毒治疗诊所接受HAART的成年人中浪费的程度,并确定相关因素。2014年3月20日至4月30日,在Hosanna镇的抗逆转录病毒疗法健康诊所对410名接受抗逆转录病毒治疗的成年人进行了基于设施的横断面研究。通过简单的随机抽样技术选择样本客户。通过面对面、使用检查表进行记录审查和体重秤测量来收集数据。使用SPSS 16版进行描述性统计、双变量和多变量逻辑回归模型,以确定与浪费相关的因素。总共有410名接受HAART的成年人参与了这项研究,其应答率为97.56%。本研究中浪费的总体程度为37.1%。食物不安全(AOR=2.1,95%CI:1.28-3.34)、多样化饮食不足(AOR=2,95%CI:1.18-3.38),低进食频率(AOR=2.2,95%CI:1.1-4.47)和机会性感染的存在(AOR=2.27,95%CI:1.47-3.49)是浪费的独立预测因素。在Hossana镇的ART诊所接受抗逆转录病毒治疗的成年人中,浪费率很高(37.1%)。抗逆转录病毒疗法干预应得到策略的支持,这些策略可以解决家庭粮食安全、营养实践以及机会性感染的预防和控制问题,以改善接受抗逆转录病毒治疗的人的健康状况。关键词:抗逆转录病毒疗法,艾滋病,消瘦,减肥,Hosanna,镇诊所。
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