A Novel Gut-Orchestrated Exercise Theory on Obesity and Cancer Prevention

Abstract

A novel gastrointestinal tract (gut) mediated exercise theory was developed to explain how highly disciplined physical activity can help prevent obesity and cancer. The gut serves the modern human body as another brain. The gut microbiota plays crucial regulatory roles in determining the health of the gut itself and entire body. Adequate exercise has been recommended to increase energy expenditure and reduce fat deposition, especially visceral adiposity. This article presents a gut-brain axis related theory based upon which with adequately intense and regular physical activity, the gut does assimilate foods and nutrients more effectively. Thus, the amount and flow of excreta are optimized. As such, the excretion of unhealthy compounds such as cholesterol, fatty acids, and to some extent starch increase. As a result, hepatic load of nutrients decrease. Consequently, the entire body tissues experience a relief in the time-consuming and energy-burning process of metabolite turnover and detoxification. Therefore, regular intense exercise does not only reduce unhealthy nutrient deposition, it can also decrease appetite and nutrient intake. This theory should permit innovative research to formulate new gut-centered public recommendations regarding the importance of adequate regular exercise to help prevent obesity and cancer and associated metabolic complexities.