Testing Toxicity and Antidote Effect of Selenium Nanoparticles with Paramecium caudatum

Khandsuren Badgar, J. Prokisch
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引用次数: 2

Abstract

A simple method for assessment of the toxicity and antidote effect of selenium nanoparticles with Paramecium caudatum is presented. Light microscopy in combination with computerized video tracking is employed for the determination of the survival time of P. caudatum. Up to 800 mg/L, selenium nanoparticles are not acutely toxic. With respect to a potential antidote effect, the lethality of silver nanoparticles, silver nitrate, sodium hydrogen selenite, and sodium selenite to P. caudatum was decreased and survival time was extended upon pre-treatment with selenium nanoparticles. Taken together, these findings suggest that administration of selenium nanoparticles attenuates exposure to toxicants. Selenium nanoparticles could be a good functional additive for food management in animals.
硒纳米粒子对草履虫的毒性及解药作用
提出了一种简单的方法来评估纳米硒对草履虫的毒性和解毒作用。采用光学显微镜结合计算机视频跟踪来测定尾状藻的生存时间。高达800 mg/L的硒纳米颗粒没有急性毒性。关于潜在的解药作用,在用硒纳米颗粒预处理后,银纳米颗粒、硝酸银、亚硒酸氢钠和亚硒酸钠对尾状藻的致死性降低,存活时间延长。总之,这些发现表明,硒纳米颗粒的给药可以减少对有毒物质的暴露。硒纳米粒子可能是一种很好的动物食品管理功能添加剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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