{"title":"Testing Toxicity and Antidote Effect of Selenium Nanoparticles with Paramecium caudatum","authors":"Khandsuren Badgar, J. Prokisch","doi":"10.4236/ojas.2021.114036","DOIUrl":null,"url":null,"abstract":"A simple method for assessment of the toxicity and antidote effect of \nselenium nanoparticles with Paramecium caudatum is presented. Light microscopy in \ncombination with computerized video tracking is employed for the determination of the survival time of P. caudatum. Up to 800 \nmg/L, selenium nanoparticles are not acutely toxic. With respect to a potential antidote effect, the \nlethality of silver nanoparticles, silver nitrate, sodium hydrogen selenite, \nand sodium selenite to P. caudatum was decreased and survival time was extended upon pre-treatment with selenium nanoparticles. \nTaken together, these findings suggest that administration of selenium \nnanoparticles attenuates exposure to toxicants. Selenium nanoparticles could be a good \nfunctional additive for food management in animals.","PeriodicalId":62784,"journal":{"name":"动物科学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"动物科学期刊(英文)","FirstCategoryId":"1091","ListUrlMain":"https://doi.org/10.4236/ojas.2021.114036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
A simple method for assessment of the toxicity and antidote effect of
selenium nanoparticles with Paramecium caudatum is presented. Light microscopy in
combination with computerized video tracking is employed for the determination of the survival time of P. caudatum. Up to 800
mg/L, selenium nanoparticles are not acutely toxic. With respect to a potential antidote effect, the
lethality of silver nanoparticles, silver nitrate, sodium hydrogen selenite,
and sodium selenite to P. caudatum was decreased and survival time was extended upon pre-treatment with selenium nanoparticles.
Taken together, these findings suggest that administration of selenium
nanoparticles attenuates exposure to toxicants. Selenium nanoparticles could be a good
functional additive for food management in animals.