A review of istent inject: A novel MIGS device in India

Abstract

Minimally invasive glaucoma surgery (MIGS) is a new ab-interno surgical procedure that aims to effectively and safely lower intraocular pressure (IOP) in open angle glaucoma (OAG). It has far less complications and recovery time compared to the traditional filtration surgeries. iStent inject is a second-generation device that allows placement of two stents in the trabecular meshwork through a single injector, thereby facilitating the reduction in IOP compared to first generation iStent that was a single stent. It works by bypassing the trabecular meshwork, which is the commonest site of outflow obstruction, to re-establish communication of aqueous humor directly with the Schlemm's canal. It is the smallest stent approved to be placed inside the human body. This review compiles publications about iStent inject highlighting its clinical efficacy as standalone procedure and with phacoemulsification, safety and cost effectiveness. This device was found to be effective and safe in the management of OAG.